Results 251 to 260 of about 215,712 (346)

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu, Chao Lei, Mukesh K Sriwastva, Ting Wang, Amanguli Tuohongerbieke, Xiaotong Song, Collin Noud, Shannon Derkson, Yi Tan, Gerald Dryden, Craig J McClain, Zhongbin Deng   +11 more
wiley   +1 more source

Prevalence of fundamental movement skill mastery in school-aged children and adolescents: a systematic review. [PDF]

BMJ Open Sport Exerc Med
Lorenzo-Martínez M, Abelairas-Gómez C, Carballo-Fazanes A, Rey E.   +3 more
europepmc   +1 more source

Special educational needs and/or disabilities training toolkit : for PGCE trainees : physical and sensory impairment : developmental coordination disorder/dyspraxia : self-study task 15 [PDF]

, 2009

core  

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

Enhancing cognitive-motor recovery in Rett syndrome: effects of integrated intervention on neuropsychological and motor outcome. [PDF]

Front Psychol
Fabio RA, Semino M, Perina M.
europepmc   +1 more source

ARL5B Drives Esophageal Squamous Cell Carcinoma Progression via ROCK1–SREBP1‐Mediated Lipid Metabolic Reprogramming

Advanced Science, EarlyView.
Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma, Yanfei Sun, Hongyuan Mao, Chenhan Huang, Zerun Li, Tianzi Wang, Dizhi Jiang, Xinyu Zhang, Zhenyu Yuan, Zhihui Zhang, Bo Cheng, Ruiqing Wang, Yufeng Cheng   +12 more
wiley   +1 more source

Impact of computerised visual-motor integration and visual perception training games on handwriting and visual skills in children with spastic cerebral palsy: study protocol for a randomised controlled trial. [PDF]

BMJ Open
Kazemnazhand Asl A, Dalvand H, Dadgar H, Khorrami-Nejad M, Rahsepar Fard K.   +4 more
europepmc   +1 more source

THE EFFECTIVENESS OF THE DEVELOPMENT OF GROSS MOTORIC SKILLS AMONG PRESCHOOL CHILDREN BETWEEN PRE AND POST STIMULATION OF TRADITIONAL ENGKLEK GAMES

Andiny Rose, Indah Rahmaningtyas, Dwi Estuning Rahayu, Sumy Dwi Antono   +3 more
openalex   +2 more sources

Effects of Parent-child Physical Activity Intervention on Gross Motor Skills among Preschoolers in China [PDF]

Zhao Jia, Borhannudin Abdullah, Roxana Dev Omar Dev, Shamsulariffin Samsudin   +3 more
openalex   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source