Results 141 to 150 of about 3,321,810 (226)

Are active video games useful in the development of gross motor skills among non-typically developing children? A meta-analysis. [PDF]

BMC Sports Sci Med Rehabil, 2022
Li S, Song Y, Cai Z, Zhang Q.
europepmc   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Effectiveness of exercise interventions on gross motor skills in children with autism spectrum disorder: a systematic review and meta-analysis. [PDF]

Front Psychiatry
Feng M, Hou Y, Zhou S, Song X.
europepmc   +1 more source

Resting state networks mediate the association between both cardiovascular fitness and gross motor skills with neurocognitive functioning. [PDF]

Child Dev, 2022
Meijer A, Königs M, Pouwels PJW, Smith J, Visscher C, Bosker RJ, Hartman E, Oosterlaan J.   +7 more
europepmc   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Gross motor skills and social behavior in childhood: a public health perspective on their developmental association. [PDF]

Front Psychol
Zhang J, Zhou Y, He R, Ye X, Chen X.
europepmc   +1 more source

Do Children with Attention Deficit and Hyperactivity Disorder Present with Different Spatio-Temporal Gait Parameters? An Evaluation of the Relationship Between Gait and Gross Motor Skills. [PDF]

Alpha Psychiatry, 2023
Demircioğlu A, Atasavun Uysal S, Şanlı Dumankaya BB, Kırdı E, Tuna Çak Esen H, Dağ O, Topuz S.   +6 more
europepmc   +1 more source

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Assessment of Gross Motor Skills Performance in Italian Children with and Without Visual Impairment. [PDF]

Children (Basel)
Castiglioni GC, Hirn G, Lippolis M, Porro M.   +3 more
europepmc   +1 more source

BRAINballs Program Improves the Gross Motor Skills of Primary School Pupils in Vietnam. [PDF]

Int J Environ Res Public Health, 2021
Pham VH, Wawrzyniak S, Cichy I, Bronikowski M, Rokita A.   +4 more
europepmc   +1 more source