Results 251 to 260 of about 970,808 (296)

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Massive aortic thrombus in a hypercoagulable patient with heparin induced thrombocytopenia: a case report. [PDF]

J Surg Case Rep
Messina JM, Pruekprasert N, Gilbert J, Sarabu M, Holmes C, Polomsky M.   +5 more
europepmc   +1 more source

AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

Advanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng, Yi Zhu, Xinrui Li, Sunxian Dai, Xiangyuan Ma, Hongwei Lu, Zhongling Wang, Benqing Zhou   +7 more
wiley   +1 more source

A Case of an Inflammatory Myofibroblastic Tumor Harboring a Novel STRN3::ALK Fusion. [PDF]

Pathol Int
Yamamoto K, Miyata R, Kunieda J, Togashi Y, Baba S, Asakawa A, Okubo K, Yamashita K, Ohashi K, Takeuchi K.   +9 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Maturation of Elasticity, Pliability and Colour of Thin Split-Thickness Skin Grafts on Deep Dermal and Muscular Wound Bed Within the Course of 1 Year. [PDF]

Int Wound J
Illg C, Gaag A, Rachunek-Medved K, Thiel JT, Daigeler A, Krauss S.   +5 more
europepmc   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Age-related prognostic disparities in cutaneous melanoma: A population-based study and validated interactive web-based nomogram for individualized prognostic stratification. [PDF]

Transl Oncol
Xu W, Zheng L, Chen Q, Luo L, He C, Chen H, Zhang J, Chen Z.   +7 more
europepmc   +1 more source

Systematic review and meta-analysis of balance training in children with developmental disorders. [PDF]

PeerJ
Nie Y, Deng N, Huang D.
europepmc   +1 more source

The First Documented Case of Ectrodactyly in Ghana: A Case Report. [PDF]

Cureus
Sobbin SJ, Hackman AE, Gyamfi FE, Kyeremeh DK, Appiagyei JD, Galley F.   +5 more
europepmc   +1 more source