Results 141 to 150 of about 8,737,298 (395)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Permafrost Table Temperature (2008–2021) in Deception Island, Antarctica

open access: yesGeoscience Data Journal
This manuscript presents a comprehensive presentation of ground temperature data collected at 16 nodes of the 121 of the Crater Lake Circumpolar Active Layer Monitoring (CALM) site on Deception Island, Antarctica, from 2008 to early 2022. Each one of the
M. A. dePablo, M. Ramos
doaj   +1 more source

Plant communities differ along socioeconomic gradients in Baltimore, MD, and Washington, D.C.

open access: yesFrontiers in Ecology and Evolution
Plants on residential urban properties can provide valuable ecosystem services or produce harmful disservices depending on fine-scale characteristics tied to plant species identity, such as growth habit or native status.
Sarah E. Rothman   +2 more
doaj   +1 more source

Cultural Jeopardy [PDF]

open access: yes, 2007
The Howard Thurman Center Student AmbassadorsBoston University's Chinese Student AssociationBoston University's UmojaBoston University's Korean Student AssociationBoston University's Minority Engineers SocietyBoston University's Japanese Student ...
Boston University Howard Thurman Center for Common Ground
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Markedness as figure-ground manipulation: a hypothesis

open access: yesCognitive Linguistics
Markedness in language has been a perpetual fascination for linguists of all persuasions, but a unified account of it has proven elusive. In this paper, I propose a figure-ground gestalt (FGG) hypothesis, arguing that markedness is a mechanism for ...
Chen Rong
doaj   +1 more source

FreeP talk: race & the media, in and out of the newsroom [PDF]

open access: yes, 2018
Panel discussion on race and the media - in and out of the newsroom, marketing materials main posterBoston University Howard Thurman Center for Common Ground, & The Daily Free ...
Boston University Howard Thurman Center for Common Ground
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy