Results 91 to 100 of about 2,760,154 (306)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Accurate determination of the Gaussian transition in spin-1 chains with single-ion anisotropy

open access: yes, 2011
The Gaussian transition in the spin-one Heisenberg chain with single-ion anisotropy is extremely difficult to treat, both analytically and numerically. We introduce an improved DMRG procedure with strict error control, which we use to access very large ...
B. Normand   +4 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Geometric Correction of PHI Hyperspectral Image without Ground Control Points

open access: yesIOP Conference Series: Earth and Environmental Science, 2014
Geometric correction without ground control points (GCPs) is a very important topic. Conventional airborne photogrammetry is difficult to implement in areas where the installation of GCPs is not available. The technical of integrated GPS/INS systems providing the positioning and attitude of airborne systems is a potential solution in such areas.
Kuifeng Luan   +5 more
openaire   +1 more source

Operational efficiency subpanel advanced mission control [PDF]

open access: yes
Herein, the term mission control will be taken quite broadly to include both ground and space based operations as well as the information infrastructure necessary to support such operations.
Friedland, Peter
core   +1 more source

Method and apparatus for producing an aircraft flare path control signal [PDF]

open access: yes, 1982
Aircraft altitude, ground velocity, and altitude rate signals are input to a computer which, using a unique control law, generates a pitch control surface command signal suitable for guiding an aircraft on its flare path to a specified runway touchdown ...
Hansen, Rolf, Lambregts, Antonius A.
core   +1 more source

Geometric Controls for a Tethered Quadrotor UAV

open access: yes, 2015
This paper deals with the dynamics and controls of a quadrotor unmanned aerial vehicle that is connected to a fixed point on the ground via a tether. Tethered quadrotors have been envisaged for long-term aerial surveillance with high-speed communications.
Lee, Taeyoung
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Automating Ground Control Point Detection in Drone Imagery: From Computer Vision to Deep Learning

open access: yesRemote Sensing
Drone-based photogrammetry typically requires the task of georeferencing aerial images by detecting the center of Ground Control Points (GCPs) placed in the field. Since this is a very labor-intensive task, it could benefit greatly from automation.
Gonzalo Muradás Odriozola   +3 more
doaj   +1 more source

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