Results 161 to 170 of about 12,842,344 (290)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Distributed multi-robot LiDAR SLAM with ground-optimized preprocessing and slope-adaptive segmentation. [PDF]

Front Neurorobot
Wang Y, Zou Q, Wang F.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Myofascial Trigger Point-Augmented Acupuncture vs Conventional Acupuncture for Early- to Mid-Stage Knee Osteoarthritis: A Randomized Clinical Trial. [PDF]

J Pain Res
Zhang L, Xu J, Jiang L, Gao K, Xue H, Li Y, Liu A, Zhang C.   +7 more
europepmc   +1 more source

THE INFLUENCE OF THE DISTRIBUTION OF GROUND CONTROL POINTS ON GEOREFERENCING

SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings, 2014
openaire   +1 more source

Five Points Lutheran, 1861-1961.

, 1961
Centennial Festivities program tipped-in at back.Cover title.Mode of access ...
Five Points Lutheran Church (Blue River, Wis.)
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission. [PDF]

NPJ Microgravity
Fredriksson R, Han Y, Du X, Sexton CA, Barasa P, Zanotti F, Hamilton NB, Ito K, Zavan B, Kozlova EN.   +9 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Dual-Model Artificial Intelligence Framework Integrating AI-Based Markerless Motion Capture for Dynamic Gait Prediction and Health-Status Classification. [PDF]

Diagnostics (Basel)
Rodríguez-Granados EJ, Urriolagoitia-Sosa G, Romero-Ángeles B, Gomez-Niebla JA, Guereca-Ibarra JR, Suarez-Hernandez ML, Rocha-Martinez MN, Carmona-Hernández EE, Lugo-Chacon LI, Ramirez-Sanchez G.   +9 more
europepmc   +1 more source