Results 131 to 140 of about 273,921 (293)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Onboard utilization of ground control points for image correction. Volume 1: Executive summary

open access: yes, 1981
Operation of a navigation system, centered around image correction, was simulated and the system performance was analyzed. Onboard utilization of ground control points for image correction is summarized. Simulation results, and recommendations for future

core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Accuracy Management of LiDAR Data Using GPS Ground Control Points

open access: yes, 2016
Nowadays, both faster and more accurate data acquisition studies are gradually gaining speed, different of traditional land surveying technics in order to obtain land data having high accuration and geometric resolution on mapping.
COŞKUN, H. Gonca   +2 more
core   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Investigation of the effect of ground control points on position accuracy in unmanned aerial vehicles photogrammetry

open access: yes, 2019
Fen Bilimleri Enstitüsü, Geomatik Mühendisliği Ana Bilim Dalıİnsansız Hava Aracı (İHA) fotogrametrisinde, yer kontrol noktasının geometrisi ve sayısı doğrudan üretilen nokta bulutunun konum doğruluğunu etkilemektedir.
Kapıcıoğlu, Hacer Şura
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

GCP Placement Methods for Improving the Accuracy of Shoreline Extraction in Coastal Video Monitoring

open access: yes한국해양공학회지
In coastal video monitoring, the direct linear transform (DLT) method with ground control points (GCPs) is commonly used for geo-rectification. However, current practices often overlook the impact of GCP quantity, arrangement, and the geographical ...
Changyul Lee   +3 more
doaj   +1 more source

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