Results 61 to 70 of about 268,517 (255)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

High-Precision Geolocation of SAR Images via Multi-View Fusion Without Ground Control Points

Remote Sensing
Synthetic Aperture Radar (SAR) images generated via range-Doppler (RD) model-based geometric correction often suffer from non-negligible systematic geolocation errors due to cumulative impacts of platform positioning inaccuracies, payload time ...
Anxi Yu, Huatao Yu, Yifei Ji, Wenhao Tong, Zhen Dong   +4 more
doaj   +1 more source

Corridor Mapping of Sandy Coastal Foredunes with UAS Photogrammetry and Mobile Laser Scanning

Remote Sensing, 2019
Recurrent monitoring of sandy beaches and of the dunes behind them is needed to improve the scientific knowledge on their dynamics as well as to develop sustainable management practices of those valuable landforms.
Alphonse Nahon, Pere Molina, Marta Blázquez, Jennifer Simeon, Sylvain Capo, Cédrik Ferrero   +5 more
doaj   +1 more source

Rectification of Bowl-Shape Deformation of Tidal Flat DEM derived from UAV Imaging

Sensors, 2020
It is necessary to periodically obtain topographic maps of the geographical and environmental characteristics of tidal flats to systemically manage and monitor them.
Hyoseong Lee, Dongyeob Han
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Bundled-Images Based Geo-Positioning Method for Satellite Images Without Using Ground Control Points

Remote Sensing
Bundle adjustment without Ground Control Points (GCPs) using stereo remote sensing images represents a reliable and efficient approach for realizing the demand for regional and global mapping.
Zhenling Ma, Yuan Chen, Xu Zhong, Hong Xie, Yanlin Liu, Zhengjie Wang, Peng Shi   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source