Results 121 to 130 of about 1,592 (218)

The Danish Out‐of‐Hospital Cardiac Arrest Trial: A Statistical Analysis Plan

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Post‐cardiac arrest care for patients resuscitated from out‐of‐hospital cardiac arrest (OHCA) includes multiple pharmacological and physiological interventions, yet optimal strategies to reduce post‐cardiac arrest syndrome–related morbidity and mortality remain uncertain.
Simon Mølstrøm, Jacob E. Møller, Henrik Schmidt, Anders M. Grejs, Steffen Christensen, Jesper Kjærgaard, Christian Hassager, Martin A. S. Meyer, Lars P. K. Andersen, Bodil S. Rasmussen, Jo B. Andreasen, Sören Möller   +11 more
wiley   +1 more source

Prophylactic Olanzapine Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest (DANOHCA) Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic strategy for delirium prevention in OHCA survivors.
Benedikte Liebetrau, Anders M. Grejs, Martin A. S. Meyer, Lars P. K. Andersen, Sören Möller, Simon Mølstrøm, Jacob E. Møller, Henrik Schmidt, Steffen Christensen, Jesper Kjærgaard, Christian Hassager, Bodil S. Rasmussen, Jo B. Andreasen   +12 more
wiley   +1 more source

Effects of Physical Activity on Brain White Matter Integrity Are Region‐, Dose‐, and Age‐Dependent: Findings From the Population‐Based Rhineland Study

Aging Cell, Volume 25, Issue 8, August 2026.
Physical activity is related to more aligned white matter fibers and microstructural reorganization of the brain. Body weight, cardiometabolic, and inflammatory factors could partly mediate the effects of physical activity on brain white matter microstructure. The effects of physical activity on the brain are age‐ and region‐specific.
Eva Saxler, Fabienne A. U. Fox, Alexandra Koch, Xingwang Yang, Weiyi Zeng, Santiago Estrada, Monique M. B. Breteler, N. Ahmad Aziz   +7 more
wiley   +1 more source

Dynamics of Body Composition and Metabolic Risk in Adolescents With Obesity Under GLP‐1 Receptor Agonist Therapy

Acta Paediatrica, Volume 115, Issue 8, Page 1726-1736, August 2026.
ABSTRACT Aim To explore changes in body composition in adolescents with obesity treated with glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) and their association with metabolic syndrome (MetS) components. Methods This real‐world retrospective study included adolescents (12–18 years) with obesity who received multidisciplinary lifestyle‐based ...
Adar Lopez, Liat Perl, Eyal Cohen‐Sela, Ophir Borger, Yael Issan, Hagar Interator, Erez Azoulay, Hadar Moran‐Lev, Ronit Lubetzky, Shira Zelber‐Sagi, Yael Lebenthal, Avivit Brener   +11 more
wiley   +1 more source

Sustained Clinical Improvement in Birch Pollen Allergy After Two Pre‐Seasonal Short Courses of Allergen‐Specific Immunotherapy: A Long‐Term Open‐Label Extension Study

Clinical &Experimental Allergy, Volume 56, Issue 8, Page 893-903, August 2026.
3 years follow‐up study to a DBPC dose‐finding trial investigating subcutaneous immunotherapy with T502 in birch‐pollen induced allergic rhinoconjunctivitis. 154 birch‐pollen allergic adults received short‐course treatment of 10,000 mTU/mL of T502 for 2 years and were observed during the next season without treatment.
Ralph Mösges, Friederike Hüffmeier, Ludger Klimek, Oliver Pfaar, Christian Neuhof, Anna Rybachuk, Cengizhan Acikel, Hacer Sahin, Silke Allekotte, Sandra del Pozo, José Luis Subiza, Miguel Casanovas, Mandy Cuevas, Laura Day, Lea Radtke, Esther Raskopf   +15 more
wiley   +1 more source

Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Olamkicept up to 2400 mg in Healthy Men: Phase I, Randomized, Placebo‐Controlled, and Double‐Blind Trial

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Olamkicept is a first‐in‐class fully human fusion protein that selectively inhibits trans interleukin (IL)‐6 signaling. Previous phase I clinical trials demonstrated that single doses up to 750 mg and multiple doses up to 600 mg were safe and well tolerated in healthy men and women.
Stanislav Ignatenko, Alla Radicke, Katharina Bruzelius, Michael Falkenberg, Lars‐Erik Kyhl, Signe Møgelmose, Arjun Ravi, Philippe Pinton   +7 more
wiley   +1 more source

Device and Data Access Considerations for Digital Health Studies Using Consumer‐Grade Wearables: An Experience‐Based Tutorial

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Consumer‐grade wearables, including smartwatches, fitness trackers, and smart rings, are accessible tools for studying pharmacologic responses in real‐time, monitoring participant health in decentralized clinical trials, optimizing outcome measures, and delivering digital interventions that promote behavior change.
Mike Zhu, Joshua D. Spencer, Sherry Chesak, Magdalena Romanowicz, Mohit Chauhan, Liselotte N. Dyrbye, Paul E. Croarkin, William V. Bobo, Arjun P. Athreya   +8 more
wiley   +1 more source

Detection and Monitoring of Topography Changes at the Tottori Sand Dune Using UAV-LiDAR. [PDF]

Sensors (Basel)
Liu J, Wu J, Okida S, Kimura R, Du M, Li Y.   +5 more
europepmc   +1 more source

Evaluation of the influence of the number of GCPS on the measurement quality of a photogrammetric block captured with an RTK UAV in geographical environments with high topographic roughness

GEOmedia
This study investigates the impact of using Ground Control Points (GCPs) on the measurement quality of photogrammetric blocks in high topographic roughness areas, captured with an RTK-enabled UAV.
Kevin De Flue Pilco Lopez, Moises Araca
doaj  

Vulcano island: the new high resolution digital surface model post 2021-2022 volcanic unrest. [PDF]

Sci Data
Bisson M, Gianardi R, Iacono F, Madonia P, De Astis G, Spinetti C.   +5 more
europepmc   +1 more source