Results 71 to 80 of about 12,614,384 (261)

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich, Franziska Friedrich, Daniel Soriano, Jona Gjeloshi, Björn C. Frye, Xuan Phuoc Nguyen, Lydia Herbstritt, Caroline von Spee‐Mayer, Britta Lang, Fabrice Nollevaux, Andreas Hoheisel, Dorothee Winterberg, Armin Braun, Thomas Epting, Christine Contini, Karl Winkler, Thomas Reinheckel, Franziska C. Trudzinski, Gernot Rohde, Daiana Stolz, Robert Bals, Martin J. Hug, Sebastian Wirtz, Christoph Peters, Carolin Jenkner   +24 more
wiley   +1 more source

A weighted least squares solution for space intersection of spaceborne stereo SAR data [PDF]

, 2001
The use of stereoscopic SAR images offers an alternative to interferometric SAR for the generation of digital elevation models (DEMs). The stereo radargrammetric method is robust and can generate DEMs of sufficient accuracy to geocode SAR images ...
Dowman, I.J., Ian J. Dowman, Pu-huai Chen, Chen, P.-H.   +3 more
core  

Table1_Using existing infrastructure as ground control points to support citizen science coastal UAS monitoring programs.docx

, 2023
Recent publications have described the ability of citizen scientists to conduct unoccupied aerial system (UAS) flights to collect data for coastal management.
Lucas F. Rabins (14819161), Ethan J. Theuerkauf (3779899), Erin L. Bunting (14819164)   +2 more
core   +1 more source

Accuracy assessment of RTK/PPK UAV-photogrammetry projects using differential corrections from multiple GNSS fixed base stations

Geocarto International, 2023
Unmanned aerial vehicles (UAVs) equipped with global navigation satellite system-real-time kinematic (GNSS RTK) receivers allow direct georeferencing of the photogrammetric project without using ground control points (GCPs).
Patricio Martínez-Carricondo, Francisco Agüera-Vega, Fernando Carvajal-Ramírez   +2 more
doaj   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

Accuracy Analysis of a Dam Model from Drone Surveys

Sensors, 2017
This paper investigates the accuracy of models obtained by drone surveys. To this end, this work analyzes how the placement of ground control points (GCPs) used to georeference the dense point cloud of a dam affects the resulting three-dimensional (3D ...
Elena Ridolfi, Giulia Buffi, Sara Venturi, Piergiorgio Manciola   +3 more
doaj   +1 more source

Sustainable Corporate Loans: A Systematic Literature Review and Future Research Agenda

Business Strategy and the Environment, EarlyView.
ABSTRACT This paper presents a systematic literature review of sustainable corporate loans (SCLs), including green loans and sustainability‐linked loans, to synthesise current academic knowledge and outline future research directions. Using a PRISMA protocol and a bibliometric analysis of 102 peer‐reviewed articles published in AJG‐ranked journals (3 ...
Md Nurul Islam Sohel, Abdullah Iqbal, Rizwan Ahmed, Vasileios Pappas   +3 more
wiley   +1 more source

A landslide monitoring method using data from unmanned aerial vehicle and terrestrial laser scanning with insufficient and inaccurate ground control points

Journal of Rock Mechanics and Geotechnical Engineering
Non-contact remote sensing techniques, such as terrestrial laser scanning (TLS) and unmanned aerial vehicle (UAV) photogrammetry, have been globally applied for landslide monitoring in high and steep mountainous areas.
Jiawen Zhou, Nan Jiang, Congjiang Li, Haibo Li   +3 more
doaj   +1 more source

Advances in Design Strategy and Mechanism Insights for Alkaline Hydrogen Evolution Reaction: Multilevel Site Engineering and Structure–Activity Relationship

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review is about material design based on engineering multilevel sites from theoretical calculation and synthetic routes to mechanism, structure–activity relationship, challenges and perspectives for boosting hydrogen production in alkaline electrolyte. Electrolytic water splitting is a clean, carbon‐free method for producing green hydrogen and has
Ke Zhang, Hongying Luo, Yudong Du, Kehao Yu, Huayu Wu, Shimin Chai, Yanyan Liu, Yongfeng Wang, Jianchun Jiang, Baojun Li   +9 more
wiley   +1 more source