Results 41 to 50 of about 2,043,430 (304)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Ground Deformation and Permafrost Degradation in the Source Region of the Yellow River, in the Northeast of the Qinghai-Tibet Plateau

Remote Sensing, 2023
The source region of the Yellow River (SRYR) is situated on the permafrost boundary in the northeast of the Qinghai-Tibet Plateau (QTP), which is an area highly sensitive to climate change. As a result of increasing global temperatures, the permafrost in
Chengye Li, Lin Zhao, Lingxiao Wang, Shibo Liu, Huayun Zhou, Zhibin Li, Guangyue Liu, Erji Du, Defu Zou, Yingxu Hou   +9 more
doaj   +1 more source

Persistent scatterer interferometry to monitor mining related ground surface deformation for data-driven modelling [PDF]

, 2006
The monitoring, interpretation and prediction of gradual ground surface deformation are critical factors in the understanding of earth systems. In many parts of the world, particularly in coastal areas where resources are often easily transportable and ...
Kemeling, Ilona
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Determination of 3D Analytical Parameters for Ground Deformation Induced by Stratum Loss during Shield Tunneling

Chengshi guidao jiaotong yanjiu
[Objective] Shield tunneling inevitably induce stratum loss, subsequently causing ground deformation. Existing analytical solutions use undetermined parameters as inputs, but the complexity of parameter determination limits the application of analytical ...
LI Xinlong, ZHOU Kai, WANG Yalei, ZHAO Jiale, LIU Yang   +4 more
doaj   +1 more source

Fault inversion contributes to ground deformation above inflating igneous sills

Volcanica, 2021
Magma emplacement is commonly accommodated by uplift of the overburden and free surface. By assuming this deformation is purely elastic, we can invert the shape and kinematics of ground deformation to model the geometry and dynamics of underlying ...
James Norcliffe, Craig Magee, Christopher Jackson, Jonas Kopping, Bailey Lathrop   +4 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Estimation of Ocean Tidal Loading Deformation From Time-Series InSAR Based on Blind Source Signal Separation and Physical Modeling

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Estimating coastal ground deformation caused by ocean tidal loading (OTL) through time-series interferometric synthetic aperture radar (InSAR) techniques is challenging but achievable.
Wei Peng, Jiachen Zhou, Wenjie Hu, Xuemin Xing, Jun Zhu, Bin Liu   +5 more
doaj   +1 more source

Multi-Sensor InSAR Assessment of Ground Deformations around Lake Mead and Its Relation to Water Level Changes

Remote Sensing, 2021
Changes in subsurface water resources might alter the surrounding ground by generating subsidence or uplift, depending on geological and hydrogeological site characteristics.
Mehdi Darvishi, Georgia Destouni, Saeid Aminjafari, Fernando Jaramillo   +3 more
doaj   +1 more source