Results 151 to 160 of about 765,164 (366)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ground effect in motorsport [PDF]
This bachelor thesis describes ground effect, its influence on car aerodynamics and its use in motorsport. The thesis describes the dependence of downforce created by ground effect on the design and set-up of the race car, as well as on the downforce ...
Mlčoch, Pavel
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The effect of egg coloration on predation of artificial ground nests
Benoı̂t Jobin, Jaroslav Picman
openalex +2 more sources
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Ground-effect is a well-known phenomenon that occurs as an aircraft approaches the surface of the earth. Flight in ground-effect changes the characteristics of the airflow around the wing causing both positive and negative effects.
Schank, Troy, Eastman, Dr. Paul
core
Computational Analysis of Pitch Stability for a Slotted Airfoil in Ground Effect
Meagan Hubbell
openalex +2 more sources
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
In an investigation into how wind turbine noise interacts with the surrounding terrain, its propagation over rough ground is simulated using a parabolic equation code using a modified effective impedance model, which characterizes the effects of a three ...
James Naylor, Qin Qin
doaj +1 more source

