Results 41 to 50 of about 2,905,272 (283)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A numerical study on heat transfer performances of horizontal ground heat exchangers in ground-source heat pumps

PLOS ONE, 2021
Horizontal ground heat exchangers (HGHEs) have advantages such as convenient construction and low cost; however, their application and popularization are restricted owing to traditional linear HGHEs occupying large space and presenting low total heat transfer capacity.
Hang Zou, Peng Pei, Chen Wang, Dingyi Hao   +3 more
openaire   +4 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Thermal design of a compact recuperative heat exchanger for a stirling engine [PDF]

, 1977
This thesis is concerned with factors affecting the thermal design of a compact recuperative type crossflowing heat exchanger for the primary heater of a Stirling engine.
Jewad, M. A.
core   +6 more sources

Oil Circulation Effects on Evaporation Heat Transfer in Brazed Plate Heat Exchanger using R134A [PDF]

, 2012
Experimental study was performed for oil circulation effects on evaporation heat transfer in the brazed type plate heat exchangers using R134A. In this study, distribution device was installed to ensure uniform flow distribution in the refrigerant flow ...
Chang, Youngsoo, Jang, Jaekyoo, Kang, Byungha   +2 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Research on the heat transfer model of double U-pipe ground heat exchanger based on in-situ testing

Frontiers in Energy Research
The Double U-pipe ground heat exchanger, known for its simple process, cost-effectiveness, high heat exchange efficiency, and low thermal resistance, remains the predominant type of ground heat exchanger in today’s shallow geothermal energy development ...
Ruifeng Wang, Ruifeng Wang, Mingchuan Shi, Ke Zhu, Ke Zhu, Jun Yu, Jun Yu, Wei Ren, Wei Ren, Guohong Yan, Guohong Yan, Zhiqiang Yin, Shujie Gao   +12 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Temperature response functions (G-functions) for single pile heat exchangers [PDF]

, 2013
Foundation piles used as heat exchangers as part of a ground energy system have the potential to reduce energy use and carbon dioxide emissions from new buildings. However, current design approaches for pile heat exchangers are based on methods developed
Loveridge, F.A., Powrie, W., Powrie, W, Loveridge, F   +3 more
core   +1 more source