Results 91 to 100 of about 142,346 (265)

含软弱土层场地地震动加速度反应谱特征周期调整方法

open access: yesDizhen xuebao
在分析场地条件对地震震害影响及国内外关于软弱土层对场地地震反应影响的基础上,采用实际含淤泥质土层场地资料,建立了12个含软弱土层的场地模型,在不同输入地震动水平下进行了场地地震反应一维等效线性化分析,讨论了软弱土层厚度和埋深对场地地震反应的影响。结果表明:随着软弱土层的埋深或厚度的增加,反应谱特征周期逐渐增大;输入地震动峰值增加,反应谱特征周期亦增大。继而依据软弱土层厚度、埋深及输入地震动强度对场地加速度反应谱特征周期的影响特征,提出了含软弱土层场地地震动加速度反应谱特征周期调整方法。
Zhen Chen   +5 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

基于KiK-net强震动记录的加速度反应谱规律性偏差

open access: yesDizhen xuebao
地震动特性受到地震震源、地震波传播介质和局部场地条件等因素的综合影响,虽然地震动反应谱虽然具有统计意义上的共性,但其具体形状又各不相同,特别是部分加速度反应谱与统计平均值之间存在显著的规律性偏差。为了进一步探究加速度反应谱与统计平均值之间的规律性偏差,本文基于日本KiK-net台网获取的8万余条强震动记录,建立了考虑地震震级和震中距影响的地面峰值加速度归一化加速度反应谱,并以预测值+0.5倍方差为界将加速度反应谱分为有、无反应谱规律性偏差的两组。通过有反应谱规律性偏差的反应谱(观测值 ...
Mingming Yuan, Xiaojun Li, Yushi Wang
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Raspberry Shake-Based Rapid Structural Identification of Existing Buildings Subject to Earthquake Ground Motion: The Case Study of Bucharest. [PDF]

open access: yesSensors (Basel), 2022
Özcebe AG   +11 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy