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Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang +10 more
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REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
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The incorporation of oxygen vacancies (OVs) presents a viable strategy for fine‐tuning the photocatalytic prowess of BiOCl. A reliable hydrogen annealing reduction technique is employed to precisely design OVs, thereby optimizing the light absorption capacity, as well as the efficiency of carrier migration and separation in BiOCl.
Shuaihao Ma +11 more
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Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen +17 more
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This paper focuses on the prediction of ground surface settlement induced by shield tunnelling in sandy cobble stratum. Based on the stochastic medium theory, an analytical solution to predict the surface settlement is developed considering the ...
Fan Wang
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Prediction of ground surface settlement by shield tunneling using XGBoost and Bayesian Optimization
Engineering Applications of Artificial Intelligence, 2022Xiaokai Niu
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The surface settlement formula of large slope tunnel is derived firstly. Then, the finite element model of shield tunnel is established by using ABAQUS software.
Yonghe Li
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A FRACTAL MODEL FOR THE TUNNELING-INDUCED GROUND SURFACE SETTLEMENT
Fractals, 2023The Gaussian function was initially adopted to model the tunneling-induced ground surface settlement, but it could not describe the porosity’s effect on the settlement. To solve the problem, Yu’s fractal theory is implemented to model the porous grand’s geometric property, and the surface settlement profile is modeled by a fractal solitary wave ...
YUAN MEI +4 more
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Characteristics of ground surface settlement during excavation
Canadian Geotechnical Journal, 1993The objective of this paper is to study the characteristics of ground surface settlement during excavation. Ten excavation cases in Taipei with good-quality construction and field observation data are selected to study the characteristics of excavation behavior.
Chang-Yu Ou +2 more
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Ground surface settlements of sands densified with explosives
Proceedings of the Institution of Civil Engineers - Ground Improvement, 2016Blast densification has long been used to densify loose, saturated sand deposits. Although it is an economically feasible approach to densify large areas, it is not widely used in engineering practice as the design is mostly empirical and some verification tests, such as the cone penetration test, standard penetration test and shear wave velocity test,
Carlos A. Vega-Posada, Richard J. Finno
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