THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
Mechanism and Control of Black Spot Deterioration on Lacquered Architectural Components of Dajue Temple. [PDF]
Ai S, Wang Y, Pan J, Hu G, Zhao R.
europepmc +1 more source
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He +9 more
wiley +1 more source
Linking satellite-derived vegetation health parameters to arborist ground observations in urban environment. [PDF]
Foltýnová L +8 more
europepmc +1 more source
Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang +3 more
wiley +1 more source
Structural and magnetic investigations of the Weyl semimetal family CeAlSi<sub>1-x</sub>Ge<sub>x</sub>. [PDF]
Mayoh DA +7 more
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Transparent Wood with Polymer-Dispersed Liquid Crystals for Next-Generation Smart Windows: Prospective for Energy Efficiency, Diurnal Light, and CO<sub>2</sub> Emission Mitigation. [PDF]
Rajan R, Shaik S.
europepmc +1 more source
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
Activin signaling inhibitor Sotatercept in pulmonary veno-occlusive disease: building a bridge to transplantation? [PDF]
Mietzner M, Held M, Pfeuffer-Jovic E.
europepmc +1 more source

