Results 81 to 90 of about 119,464 (301)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

DIAGNOSTICS, RELIABILITY IMPROVEMENT AND A RESIDUAL RESOURCE OF SOME PROTECTION SYSTEMS

Известия высших учебных заведений: Нефть и газ, 2015
This article contains the material on some features of a grounding device and on calculation of lightning protection resource.
I. S. Sukhachev, O. V. Smirnov, S. V. Vorobjeva, T. V. Mikhaleva   +3 more
doaj   +1 more source

The ATLAS SCT grounding and shielding concept and implementation [PDF]

, 2012
This paper presents a complete description of Virgo, the French-Italian gravitational wave detector. The detector, built at Cascina, near Pisa (Italy), is a very large Michelson interferometer, with 3 km-long arms. In this paper, following a presentation
Bernabeu, J, Hessey, N P, Greenhall, A., Feld, L, Civera, J V, Moorhead, GF, Peeters, SJM, Sanchez, J., Kondo, Toshiaki, Bates, R.L., Martinez-McKinney, F, Moorhead, G F, Bruckman de Renstrom, P A, Grillo, A.A., Gruwe, M, Oshea, V., Bell, P J, Gonzalez, F., Stastny, J, Tyndel, M, Gruwe, M., Weidberg, AR, Bell, PJ, Wilmut, I, Morrissey, M C, Mikulec, B, Gadomski, S., Wallny, R., Werneke, P, Unno, Y., Peeters, S J M, Hessey, NP, Cindro, V., Sanchez, Jose Javier, Greenhall, A, Pater, J. R., Gonzalez, Francisco, Dolezal, Z, Hessey, N. P., McPherson, A, Tarrant, J, Lozano Bahilo, J., McMahon, SJ, Feld, Lutz, de Renstrom, PAB, Bruckman de Renstrom, P. A., Terada, S, Nichols, A, Mikus, M, Kohriki, T., Martinez-McKinney, F., Wallny, R, Kodys, P., Gadomski, S, Civera, J. V., Spencer, E, Ciocio, A., Bohm, J, Grillo, AA, Perrin, E, Ikegami, Y, Gornicki, E., Ikegami, Y., Bell, P. J., Pater, J R, de Renstrom, P. A. Bruckman, Phillips, P. W., Wilmut, I., Weidberg, A.R., Pieron, J. P., Spencer, E., McMahon, S.J., Grillo, A A, Gornicki, E, Wells, P.S., Pernegger, H, Dervan, P., Koperny, S, Grosse-Knetter, J., Nichols, A., O'Shea, V., Hessey, N.P., Civera, J.V., Tyndel, M., Lacasta, C, O'Shea, V, Brenner, R., Lacasta, C., Peeters, S.J.M., Mikuzcaron, M., Pater, J.R., Weber, M, Pernegger, H., Terada, S., Bates, R. L., Unno, Y, Moorhead, G. F., Roe, S, McPherson, A., Gonzalez, F, Pater, JR, Phillips, P.W., Catinaccio, A., Brenner, R, Cindro, V, Dick, B, Weidberg, A. R., Nagai, K, Moorhead, G.F., Roe, S., Werneke, P., Mcmahon, S. J., Jones, TJ, Bates, RL, Morrissey, M. C., Pieron, J P, Haywood, S., Wells, P. S., Peeters, S. J. M., Jones, T. J., Wells, P S, Feld, Lars P., Feld, L., Bohm, J., Phillips, PW, Mikulec, B., Mikuz, M, Haywood, S, McMahon, S J, Morrissey, M.C., Kondo, T., Ferrere, D., Ferrere, D, Weber, M., Civera, JV, Sanchez, J, Bizzell, J, Stastny, J., Chouridou, S, Malecki, P., Kaplon, J., Dick, B., Koperny, S., Ciocio, A, Wells, PS, Jones, T.J., Tarrant, J., Bell, P.J., Pieron, J.P., Grosse-Knetter, J, Kaplon, J, Dolezal, Z., Bizzell, J., Eklund, L, Mikuž, M., Dervan, P, Jones, T J, Catinaccio, A, Grillo, A. A., Phillips, P W, Kodys, P, Pieron, JP, Eklund, L., Chouridou, S., Bahilo, J.L., Malecki, P, Kohriki, T, Weidberg, A R, Perrin, E., Lozano Bahilo, J, Nagai, K., Morrissey, MC, Bernabeu, J., Bruckman de Renstrom, P.A., Kondo, T   +174 more
core   +1 more source

Euthanasia: above ground, below ground [PDF]

Journal of Medical Ethics, 2004
The key to the euthanasia debate lies in how best to regulate what doctors do. Opponents of euthanasia frequently warn of the possible negative consequences of legalising physician assisted suicide and active euthanasia (PAS/AE) while ignoring the covert practice of PAS/AE by doctors and other health professionals.
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Grounding grounds necessity

Analysis, 2020
Abstract Drawing from extensions of existing ideas in the logic of ground, a novel account of the grounds of necessity is presented, the core of which states that necessary truths are necessary because they stand in specific grounding connections.
openaire   +2 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Intrinsicality, Independence and Grounding [PDF]

, 2020
This paper investigates the plausibility of Witmer, Butchard and Trogdon’s (2005) proposal to distinguish intrinsic properties from extrinsic ones in terms of independence from accompaniment and grounding.
Allen
core   +1 more source

Common ground and grounds of law [PDF]

Journal of Legal Philosophy, 2020
A central premise of Ronald Dworkin’s famous Argument from Theoretical Disagreement is that judges regularly disagree about the grounds of law. The occurrence of these so-called ‘theoretical disagreements’, it is argued, cannot be explained by the influential legal positivist theory of HLA Hart according to which the grounds of law are constituted by ...
openaire   +1 more source