Results 71 to 80 of about 127,244 (292)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Incompatibilism and the Principle of Sufficient Reason in Kant’s 'Nova Dilucidatio'

Journal of Modern Philosophy, 2022
The consensus is that in his 1755 'Nova Dilucidatio', Kant endorsed broadly Leibnizian compatibilism, then switched to a strongly incompatibilist position in the early 1760s.
Aaron Wells
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Lightning‐Induced Overvoltage on Overhead Distribution Line via Hybrid MTL‐PEEC Method

High Voltage
Transient simulation are more economical and adaptable means of studying lightning overvoltage for overhead distribution line system compared to experiments. A hybrid multi‐transmission‐line (MTL)‐partial element equivalent circuit (PEEC) method proposed
Runyu Fu, Jinxin Cao, Yating Zhao, Jianguo Wang, Yaping Du, Li Cai, Mi Zhou, Yuxuan Ding   +7 more
doaj   +1 more source

Death Ground [PDF]

Extended Abstracts of the 2019 CHI Conference on Human Factors in Computing Systems, 2019
Death Ground is a competitive musical installation-game for two players. The work is designed to provide the framework for the players/participants in which to perform game-mediated musical gestures against each-other. The main mechanic involves destroying the other player's avatar by outmaneuvering and using audio weapons and improvised musical ...
Christos Michalakos, Bernt Isak Wærstad
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Discussion on circuit design for reducing coupling degree of interference source

Gong-kuang zidonghua, 2014
Some main ways of interference coupling in electronic circuit design process were described and their caused factors were analyzed briefly. How to reduce interference source coupling degree in the circuit design process were discussed from aspects of ...
YAN Gangfeng, FANG Hong, YANG Wei, GUO Bing   +3 more
doaj   +1 more source

Grounding grounds necessity

Analysis, 2020
Abstract Drawing from extensions of existing ideas in the logic of ground, a novel account of the grounds of necessity is presented, the core of which states that necessary truths are necessary because they stand in specific grounding connections.
openaire   +2 more sources