Results 31 to 40 of about 6,825 (217)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Observation of an upward lightning flash with 21 upward positive leaders initiated from different wind turbines in wind farm

High Voltage
As the wind turbine height increases, the probability of multiple upward leaders flashes within the wind farm increases. In this study, an upward lightning flash containing 21 upward positive leaders (UPLs) initiated from different wind turbines in ...
Li Cai, Yifeng Ke, Wenchao Fan, Ruisheng Yan, Mi Zhou, Jianguo Wang, Yadong Fan   +6 more
doaj   +1 more source

Prediction of Breakdown Voltage of Long Air Gaps Under Switching Impulse Voltage Based on the ISSA-XGBoost Model

Energies
In transmission lines, the discharge characteristics of long air gaps significantly influence the design of external insulation. Existing machine learning models for predicting breakdown voltage are typically limited to single gaps and do not account for
Zisheng Zeng, Bin Song, Shaocheng Wu, Yongwen Li, Deyu Nie, Linong Wang   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Differences in M‐components between triggered lightning striking the ground and overhead line

High Voltage
In the summer of 2018–2019, rocket‐triggered lightning experiments were conducted in Guangzhou, China. There were two types of lightning targets: ground and overhead line.
Li Cai, Yiyang Du, Wenchao Fan, Mi Zhou, Jianguo Wang, Jinxin Cao, Yadong Fan   +6 more
doaj   +1 more source

The Mitigation of Interference on Underground Power Lines Caused by the HVDC Electrode

Energies, 2023
High Voltage Direct Current power links are usually designed to adopt, on a continuous basis or during emergency operations, two grounding plants using the soil or seawater as a link–current return path.
Massimo Brignone, Daniele Mestriner, Paolo Molfino, Mario Nervi, Massimo Marzinotto, Sino Patti   +5 more
doaj   +1 more source

Empirically grounding grounded cognition: The case of color [PDF]

NeuroImage, 2014
Grounded cognition theories hold that the neural states involved in experiencing objects play a direct functional role in representing and accessing object knowledge from memory. However, extant data marshaled to support this view are also consistent with an opposing view that perceptuo-motor activations occur only following access to knowledge from ...
Ben D. Amsel, Thomas P. Urbach, Marta Kutas   +2 more
openaire   +3 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Relationship between radar reflectivity thresholds and very low frequency/low frequency total lightning for thunderstorm identification

High Voltage
To improve our knowledge of the spatio‐temporal correspondence between radar reflectivity and VLF/LF total lightning data, this paper proposes indexes to quantify the horizontal distribution and temporal evolution characteristics between radar composite ...
Yijun Huang, Jianguo Wang, Li Cai, Yadong Fan, Hongbin Wang, Tao Zhang   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source