Results 61 to 70 of about 412,086 (307)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

GROUNDING IN FACE-TO-FACE CONVERSATION: AN ETHNOGRAPHY STUDY [PDF]

open access: yes, 2014
Grounding is the process of achieving mutual understanding or belief about what was said between participants in a conversation. Its role is of a paramount important in communication to succeed.
Kamiluddin, Udin
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Framework of Social Ontology

open access: yesRUDN Journal of Philosophy, 2022
The research sets out an organizing framework for the field of social ontology, the study of the of the nature of the social world. Social ontology is also gaining prominence in traditional philosophical discussions. The subject matter of social ontology
B. Epstein   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

B. Epstein’s Social Ontology

open access: yesRUDN Journal of Philosophy, 2022
The article realizes the analysis of B. Epstein’s social ontology. Social ontology is teaching on basic principles of constructing of social reality, founded on interdisciplinary and transdisciplinary strategies of investigations of the social world ...
Andrey M. Orekhov
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Lightning‐Induced Overvoltage on Overhead Distribution Line via Hybrid MTL‐PEEC Method

open access: yesHigh Voltage
Transient simulation are more economical and adaptable means of studying lightning overvoltage for overhead distribution line system compared to experiments. A hybrid multi‐transmission‐line (MTL)‐partial element equivalent circuit (PEEC) method proposed
Runyu Fu   +7 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Discussion on circuit design for reducing coupling degree of interference source

open access: yesGong-kuang zidonghua, 2014
Some main ways of interference coupling in electronic circuit design process were described and their caused factors were analyzed briefly. How to reduce interference source coupling degree in the circuit design process were discussed from aspects of ...
YAN Gangfeng   +3 more
doaj   +1 more source

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