Results 51 to 60 of about 30,616 (269)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Simulation Analysis of Single-phase Grounding Fault of Resonant Grounding System

open access: yesGong-kuang zidonghua, 2012
For problem of difficult line selection caused by small current of fault line with uncertain direction when single-phase grounding fault happens in resonant grounding system, the paper theoretically analyzed change law of zero-sequence voltage and zero ...
LI Hui, TANG Yi, SUN Chang-qing
doaj  

The point ground electrode in vicinity of the semi-spherical inhomogenity [PDF]

open access: yesSerbian Journal of Electrical Engineering, 2005
Characterization of the point ground electrode placed in the surroundings or inside of the semi-spherical earth inhomogenity and fed by low frequency (LF) current using isolated earthling conductor, is presented in this paper.
Cvetković Nenad N., Rančić Predrag D.
doaj   +1 more source

The Power of Ground User in Recommender Systems

open access: yesPLoS ONE, 2013
Accuracy and diversity are two important aspects to evaluate the performance of recommender systems. Two diffusion-based methods were proposed respectively inspired by the mass diffusion (MD) and heat conduction (HC) processes on networks. It has been pointed out that MD has high recommendation accuracy yet low diversity, while HC succeeds in seeking ...
Zhou, Yanbo   +3 more
openaire   +6 more sources

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

PAST: Programa para el proyecto y análisis de sistemas de puesta a tierra. (Primera parte); SistPTEx: Program for the project and analysis of grounding system. (First part).

open access: yesRevista Científica de Ingeniería Energética, 2011
resistencia de contacto a tierra de diferentes configuraciones de electrodos, desde métodos aproximados, métodos semiexactos, hasta métodos que garantizan muy buenos niveles de exactitud.
Angel Cecilio Valcárcel Rojas   +2 more
doaj  

Advancing Grounding System Design: A Comprehensive Review of Key Elements, Parameters, and Performance Insights

open access: yesIEEE Access
The design of high-performance grounding systems is a cornerstone of safety and reliability in modern AC substations, particularly under increasingly severe fault and transient operating conditions.
Mahmoud Wahba   +3 more
doaj   +1 more source

Learning to Ground in Spoken Dialogue Systems [PDF]

open access: yes2007 IEEE International Conference on Acoustics, Speech and Signal Processing - ICASSP '07, 2007
Machine learning methods such as reinforcement learning applied to dialogue strategy optimization has become a leading subject of researches since the mid 90's. Indeed, the great variability of factors to take into account makes the design of a spoken dialogue system a tailoring task and reusability of previous work is very difficult.
openaire   +2 more sources

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