Results 51 to 60 of about 9,005,192 (299)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Grounding Gene Mentions with Respect to Gene Database Identifiers [PDF]
, 2004 We describe our submission for task 1B of the BioCreAtIvE competition which is concerned with grounding gene mentions with respect to databases of organism gene identifiers.
Nguyen, Huy +4 more
core
Interconnections criteria of grounding grids in global grounding systems
, 2018 A Global Grounding System is defined as the combination of local grounding systems, obtained by their interconnection, which ensures, thanks to their proximity, that no dangerous touch voltages can arise.
S. Mangione +7 more
core +1 more source
Applied SciencesDesigning and installing efficient grounding systems in power distribution networks is considered a complex and crucial task to ensure the reliable operation of power-protective schemes while mitigating hazardous potentials arising from faults, thereby ...
Emmanouil D. Ellinas +4 more
doaj +1 more source
Machines, 2023 A multiphase rectifier generator is important power generation equipment in DC power systems in transportation fields such as ships and aviation. Grounding design and grounding fault detection and positioning are key technologies for the safe operation ...
He Huang +4 more
doaj +1 more source
The Metalogic of Ground: Pure and Iterative Systems
Journal of Philosophical Logic, 2022 AbstractI develop a graph-theoretic model theory for pure and iterative grounding logics.
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Grounding and Aristotle’s Posterior Analytics [PDF]
Fabrice Correia and Benjamin Schnieder suggest that Aristotle’s account of formal causation in the Posterior Analytics is a type of grounding. While there are many similarities, I will argue that what Aristotle had in mind differs from contemporary ...
Sandstad, Petter
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source