Results 31 to 40 of about 19,231 (267)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Grounding Fault Protection Scheme for 0.4 kV Switchgear in Metro Substations

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Single-phase grounding faults account for over 80% of the total distribution line faults, with most inter-phase faults originating from single-phase grounding faults.
ZHOU Wenwei
doaj   +1 more source

A Method for Calculating Grounding Resistance of Reinforced Concrete Foundation Grounding Systems

open access: yesEnergies, 2022
Tower foundations have been used as grounding electrodes to reduce the area of the grounding devices. However, it is difficult to calculate the grounding resistance due to the complex structure of the reinforced concrete foundation.
Bowen Dou, Rui Liu, Youping Tu, Bo Zhang
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

The Impact of Substation Grounding Grid Design Parameters in Non-Homogenous Soil to the Grid Safety Threshold Parameters

open access: yesIEEE Access, 2021
It is important to ensure that a grounding system is designed with a low magnitude of earth resistance, so the protection system can divert the large fault current to earth effectively.
Navinesshani Permal   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Back-flashover Investigation of HV Transmission Lines Using Transient Modeling of the Grounding Systems

open access: yesIranian Journal of Electrical and Electronic Engineering, 2016
The article presents the transients analysis of the substation grounding systems and transmission line tower footing resistances which can affect to the back-flashover (BF) or overvoltage across insulator chain in an HV power systems by using EMTP-RV ...
F. Amanifard, N. Ramezani
doaj  

Power system neutral point grounding

open access: yesJournal of Energy - Energija, 2022
The method used for neutral point grounding is very important for power network operation. There are many ways of grounding, which are used in practice, and the decision on the method of neutral grounding depends on the situation in the network connected to the substation.
DRANDIĆ, ANA   +3 more
openaire   +4 more sources

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