Results 51 to 60 of about 1,195,505 (315)

Effects of Small-Sided Games vs. Running-Based High-Intensity Interval Training on Physical Performance in Soccer Players: A Meta-Analytical Comparison

Frontiers in Physiology, 2021
Objectives: This systematic review with meta-analysis (SRMA) was conducted to compare the effects of SSG-based interventions vs. running-based HIIT interventions on soccer players' sprinting time (ST), vertical height jump (VJH), and change of direction ...
Filipe Manuel Clemente, Filipe Manuel Clemente, Rodrigo Ramirez-Campillo, Rodrigo Ramirez-Campillo, José Afonso, Hugo Sarmento   +5 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Technology-based group exercise interventions for people living with dementia or mild cognitive impairment: a scoping review protocol

BMJ Open, 2022
Introduction More than 50 million people worldwide are living with dementia in 2020, and this number is expected to double every 20 years. Physical exercise is a growing field in non-pharmacological interventions for dementia care.
Lillian Hung, Juyoung Park, Hannah Levine, Paavan Randhawa   +3 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The Phase Model of Misinformation Interventions [PDF]

Proc. ACM Hum.-Comput. Interact. 9, 2, Article CSCW190 (April 2025), 28 pages
Misinformation is a challenging problem. This paper provides the first systematic interdisciplinary investigation of technical and non-technical interventions against misinformation. It combines interviews and a survey to understand which interventions are accepted across academic disciplines and approved by misinformation experts.
arxiv   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

FEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann   +4 more
wiley   +1 more source

Clinical and cost-effectiveness of parenting intervention for mothers experiencing psychosocial stress: insights from the early closure of the Mellow Babies RCT

Public Health Research
Background Problems in children’s early social and emotional development are likely to have major long-term consequences for the individual and society: maternal emotional well-being is associated with better outcomes.
Lucy Thompson, Jessica Tanner, Matthew Breckons, Naomi Young, Laura Ternent, Thenmalar Vadiveloo, Philip Wilson, Danny Wight, Louise Marryat, Iain McGowan, Graeme MacLennan, Angus MacBeth, James McTaggart, Tim Allison, John Norrie   +14 more
doaj   +1 more source

Comparing the effectiveness of group-based exercise to other non-pharmacological interventions for chronic low back pain: A systematic review.

PLoS ONE, 2020
BackgroundLow back pain (LBP) is the leading cause of disability worldwide with a substantial financial burden on individuals and health care systems.
James Lemieux, Vahid Abdollah, Brandyn Powelske, Greg Kawchuk   +3 more
doaj   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

FEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Community-based group physical activity and/or nutrition interventions to promote mobility in older adults: an umbrella review

BMC Geriatrics, 2022
Background Physical activity and a healthy diet are important in helping to maintain mobility with aging. This umbrella review aims to identify group-based physical activity and/or nutrition interventions for community-dwelling older adults that improve ...
Sarah E. Neil-Sztramko, Kylie Teggart, Caroline Moore, Diana Sherifali, Donna Fitzpatrick-Lewis, Giulia Coletta, Stuart M. Phillips, K. Bruce Newbold, Elizabeth Alvarez, Ayse Kuspinar, Courtney C. Kennedy, Pasqualina L. Santaguida, Rebecca Ganann   +12 more
doaj   +1 more source