Results 81 to 90 of about 4,194,275 (243)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
ReligionsThere are discriminatory, structured, opaque human rights violations that keep the socioeconomically vulnerable subservient, a social problem that goes against the core Christian principle: humans are created in the image of God and all share equal ...
Santhosh-Kumar Appu
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Medical Journal of BabylonBackground: Acute myocardial infarction (AMI) is considered one of the most threatening cardiovascular diseases, also called a heart attack, which occurs when there is a blockage in the blood flow to the heart muscle.
Ahmed F. F. Al-Baaj +3 more
doaj +1 more source
Frames of Group Sets and Their Application in Bundle Theory
MathematicsWe study fiber bundles where the fibers are not a group G but a free G-space with disjoint orbits. The fibers are then not torsors but disjoint unions of these; hence, we like to call them semi-torsors.
Eric J. Pap, Holger Waalkens
doaj +1 more source
Endocrinology Research and Practice, 2023 Objective: Energy deprivation induces changes in various components of the “growth hormone”/“insul in-like growth factor-I” axis; however, it remains unclear whether Ramadan fasting could alter which ones in response to food deprivation.
Majid Reza Sheikh Rezaee +4 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Jurnal Antropologi: Isu-Isu Sosial Budaya, 2017 The debate on the involvement of youth in music is not a new topic in the discourses on youth and life styles. The article discusses a research work on a group of Malay urban youth in Malaysia who were involved in underground rock music and the ...
Rokiah Ismail
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source