Results 111 to 120 of about 27,019,645 (348)

Hyper-Kamiokande Physics Opportunities [PDF]

open access: yes, 2016
We propose the Hyper-Kamiokande (Hyper-K) detector as a next generation un- derground water Cherenkov detector. It will serve as a far detector of a long base- line neutrino oscillation experiment envisioned for the upgraded J-PARC beam, and as a ...
Group, TH-KW
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Group Anonymity

open access: yes, 2010
In recent years the amount of digital data in the world has risen immensely. But, the more information exists, the greater is the possibility of its unwanted disclosure. Thus, the data privacy protection has become a pressing problem of the present time.
Chertov, Oleg, Tavrov, Dan
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

East Midlands urban action plan 2005-2011 [PDF]

open access: yes, 2005
This is the second urban action plan (UAP) for the East Midlands. The plan sets out a framework for urban renaissance in the East Midlands and provides a delivery plan that includes significant schemes in the priority urban areas that will influence the ...
Urban Partnership Group
core  

The Automorphism Group of Hall's Universal Group

open access: yes, 2017
We study the automorphism group of Hall's universal locally finite group $H$. We show that in $Aut(H)$ every subgroup of index $< 2^\omega$ lies between the pointwise and the setwise stabilizer of a unique finite subgroup $A$ of $H$, and use this to ...
Paolini, Gianluca, Shelah, Saharon
core   +1 more source

Braid Groups are Linear Groups

open access: yesAdvances in Mathematics, 1996
Let \(B_n\) denote the braid group on \(n\) strings. \(B_2\) is infinite cyclic and hence is a linear group. It is well-known that \(B_3\) is also a linear group. But it has remained an open problem as to whether any other braid groups are linear.
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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