Results 231 to 240 of about 41,735,200 (392)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effects of Psyllium Husk on Metabolic Regulators, Insulin Resistance, and SIRT6 in Liver and Muscle of Type 2 Diabetic Rats. [PDF]

Vet Med Sci
Ümit F, Çiftci G, Onuk B, Aci R, Çaka Ö, Çiftci A.   +5 more
europepmc   +1 more source

Methanogens: reevaluation of a unique biological group

Microbiological reviews, 1979
W. Balch, G. Fox, L. Magrum, C. Woese, R. Wolfe   +4 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Effect of Integrated Lifestyle Intervention Incorporating Calorie-Carbohydrate Restriction With or Without Time-Restricted Feeding for Remission of Type 2 Diabetes (DIREM): A Single Blind Randomised Controlled Trial. [PDF]

Endocrinol Diabetes Metab
Badrooj N, Esteghamati A, Djafarian K, Yekaninejad MS, Mohammadpour S, Dankoob V, Reyhan SK, Abbaszade M, Emamgholipour S, Shab-Bidar S.   +9 more
europepmc   +1 more source

The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group.

New England Journal of Medicine, 1993
E. Lewis, L. Hunsicker, R. Bain, R. Rohde   +3 more
semanticscholar   +1 more source

Erratum: “The ε Chamaeleontis Young Stellar Group and the Characterization of Sparse Stellar Clusters” (ApJ, 599, 1207 [2003]) [PDF]

, 2006
Eric D. Feigelson, W. A. Lawson, G. P. Garmire   +2 more
openalex   +1 more source

Nepal: From People Power to Peace? [PDF]

, 2006
International Crisis Group
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

On differential operators permutable with Lie continuous groups of transformations [PDF]

, 1937
Kôshichi Toyoda
openalex   +1 more source