Results 181 to 190 of about 13,701,338 (294)

FGF23 promotes atrial fibrillation susceptibility through ETV1-dependent sodium channel regulation and calcium handling abnormalities. [PDF]

Exp Physiol
Yu Q, Zeng L, Chen Z, Lin Z, Wang C, Wang L, Fu H, Zhang J.   +7 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Substrate-Dependent Pro- and Antiarrhythmic Action of Omecamtiv Mecarbil at the Ventricular and Atrial Level: Insights from a Langendorff-Perfused Rabbit Heart Model. [PDF]

Cardiovasc Toxicol
Wolfes J, Neff K, Wegner F, Rath B, Doldi F, Eckardt L, Frommeyer G, Ellermann C.   +7 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance. [PDF]

Adv Sci (Weinh)
Gao Y, Chu G, Jiao W, Zhong Y, Yuan H, Li C, Li J, Wang S, Guan B, Zhao J, Pan L, Niu H, Li J.   +12 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Common sense oncology values to action: a patient-led framework for randomized clinical trial design. [PDF]

J Natl Cancer Inst
Tregear ML, Verduzco-Aguirre HC, Shkabari B, Koven R, Scowcroft H, Venkatash V, Brundage MD, Chidebe RCW, Eisenhauer EA, Gyawali B, Sirohi B, Booth CM, Jackson CGCA.   +12 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Unpacking Multimodal Verb Input in English: Insights From Typically Developing Infants and Those Who are Deaf and Hard of Hearing. [PDF]

Infancy
Meng F, Horsfall-Turner I, Hussain C, Nomikou I, Abu-Zhaya R.   +4 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source