Results 161 to 170 of about 511,555 (281)

TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy

open access: yesBrain Pathology, EarlyView.
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin   +14 more
wiley   +1 more source

New biosensors and transgenic mice for multiplex cGMP imaging

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters   +6 more
wiley   +1 more source

Survey‐Based Research for Creativity and Innovation Management: Review and Recommendations

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Survey methodology remains a widely used data collection method in creativity and innovation management studies. However, evolving technological advancements and methodological challenges necessitate a reassessment of best practices to benefit the most from it.
Marco Mismetti   +2 more
wiley   +1 more source

Computing Skinning Weights via Convex Duality

open access: yesComputer Graphics Forum, EarlyView.
We present an alternate optimization method to compute bounded biharmonic skinning weights. Our method relies on a dual formulation, which can be optimized with a nonnegative linear least squares setup. Abstract We study the problem of optimising for skinning weights through the lens of convex duality.
J. Solomon, O. Stein
wiley   +1 more source

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