Results 51 to 60 of about 32,895 (317)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Simplicial complexes in network intrusion profiling: pattern construction through simplicial centralities

open access: yesApplied Network Science
For studying intrusion detection data we consider data points referring to individual IP addresses and their connections. We build networks represented by graphs associated with those data points, such that vertices in a graph are constructed to denote ...
Mandala von Westenholz   +2 more
doaj   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

open access: yesAdvanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang   +10 more
wiley   +1 more source

Expanders In Group Algebras [PDF]

open access: yesCOMBINATORICA, 2004
Let G be a finite group and let p be a prime such that (p, |G|) = 1. We study conditions under which the Abelian group $$\Bbb F$$ p [G] has a few G-orbits whose union generate it as an expander (equivalently, all the discrete Fourier coefficients (in absolute value) of this generating set are bounded away uniformly from one).We prove a (nearly sharp ...
Roy Meshulam, Avi Wigderson
openaire   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai   +13 more
wiley   +1 more source

Physics‐Constrained Constitutive Learning of Rate‐Limiting Timescales for Efficient Hydrogen‐Based Direct Reduction for Green Steel Making

open access: yesAdvanced Science, EarlyView.
A conversion‐resolved constitutive framework is developed for the hydrogen‐based direct reduction of iron oxide pellets. Effective reaction and transport timescales are inferred directly from measured trajectories and mapped against operating conditions, pellet architecture, and composition. The analysis reveals how late‐stage transport control emerges
Anurag Bajpai   +3 more
wiley   +1 more source

Group algebras and algebras of Golod-Shafarevich [PDF]

open access: yesProceedings of the American Mathematical Society, 1987
In [2], Golod, using results of Golod and Shafarevich [1], has constructed a finitely generated algebra A = K ⟨ y 1 , … , y d
openaire   +2 more sources

Updatable Closed‐Form Evaluation of Arbitrarily Complex Multiport Network Connections

open access: yesAdvanced Electronic Materials, EarlyView.
The inverse design of electrically large wave devices often uses reduced‐order multiport models with discrete optimization, requiring many evaluations of complex interconnections between subsystems that differ only in a few blocks. This paper introduces a closed‐form framework enabling efficient Woodbury low‐rank updates of related, previous ...
Hugo Prod'homme, Philipp del Hougne
wiley   +1 more source

The Classification, Automorphism Group, and Derivation Algebra of the Loop Algebra Related to the Nappi–Witten Lie Algebra

open access: yesJournal of Mathematics, 2021
Set L≔H4⊗ℂR, R≔ℂt±1, and S≔ℂt±1/mm∈ℤ+. Then, L is called the loop Nappi–Witten Lie algebra. R-isomorphism classes of S/R forms of L are classified. The automorphism group and the derivation algebra of L are also characterized.
Xue Chen
doaj   +1 more source

Description of the automorphism groups of some Leibniz algebras

open access: yesResearches in Mathematics, 2023
Let $L$ be an algebra over a field $F$ with the binary operations $+$ and $[,]$. Then $L$ is called a left Leibniz algebra if it satisfies the left Leibniz identity: $[[a,b],c]=[a,[b,c]]-[b,[a,c]]$ for all elements $a,b,c\in L$.
L.A. Kurdachenko, O.O. Pypka, M.M. Semko
doaj   +1 more source

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