Results 131 to 140 of about 15,078,195 (279)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A Bayesian Model of Group Decision-Making
Operations Research and Decisions, 2016 A change in the opinion of a group, treated as a network of communicating agents, caused by the accumulation of new information is expected to depend on communication within the group, cooperation and, possibly, a kind of conformity mechanism.
Tadeusz Wibig +2 more
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Trust-driven consensus reaching in human-AI hybrid large-scale group decision-making. [PDF]
Front Artif IntellWang X, Xu X, Zhang W.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Integrating Consensus-Based Group Decision Making into the Graph Model for Conflict Resolution in Complex Conflict Environments. [PDF]
Entropy (Basel)Zhang H, Lu X, Wang F.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
State-dependent value representation: Evidence from the striatum
Frontiers in Neuroscience, 2014 Christopher J Burke +4 more
doaj +1 more source
Shared emotions, interpersonal syntonization, and group decision-making: a multi-agent perspective. [PDF]
Front Neurosci, 2023 Crivelli D, Balconi M.
europepmc +1 more source