Results 51 to 60 of about 4,507,496 (290)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Universal size effects for populations in group-outcome decision-making problems

, 2013
Elections constitute a paradigm of decision-making problems that have puzzled experts of different disciplines for decades. We study two decision-making problems, where groups make decisions that impact only themselves as a group.
Borghesi, Christian, Caparros, Fabrice, Hernández, Laura, Louf, Rémi   +3 more
core   +3 more sources

Effect of playing computer games on decision making in people with intellectual disabilities [PDF]

, 2008
People with intellectual disabilities have difficulty making decisions and this may hinder their independence and inclusion in society. Interactive computer software may give them the opportunity to practice the underlying components of this skill.
Brown, DJ, Rees, F, Standen, PJ
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

A multi-agent system to support location based group decision making in mobile teams [PDF]

, 2003
This paper describes an agent-based approach for developing a location-based asynchronous group decision-support system for mobile teams. The approach maximises the use of reusable service components (GSCmas — generic service component for multi-agent ...
Buckland, MA, Lee, H, Shepherdson, JW
core   +1 more source

Observing Group Decision Making Processes

Proceedings of the 10th ACM Conference on Recommender Systems, 2016
Most research on group recommender systems relies on the assumption that individuals have conflicting preferences; in order to generate group recommendations the system should identify a fair way of aggregating these preferences. Both empirical studies and theoretical frameworks have tried to identify the most effective preference aggregation ...
Amra Delic, Julia Neidhardt, Thuy Ngoc Nguyen 0001, Francesco Ricci 0001, Laurens Rook, Hannes Werthner, Markus Zanker   +6 more
openaire   +3 more sources

Progress towards the Sustainable Development Goal 14 (Life below water) in the context of Brazil: A multicriteria approach

Sustainable Futures
The oceans are a source of various essential resources for daily life, such as tourism and fishing. Brazil possesses thousands of kilometers of coastline, enjoying it with various activities such as fishing, tourism, and transportation. The importance of
Vinicius Moretti, Natália Ramos Corraini, Everton Luiz Melo, Marinez Eymael Garcia Scherer, João Carlos Colmenero   +4 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Socioscientific decision making in the science classroom: the effect of embedded metacognitive instructions on students' learning outcomes [PDF]

, 2013
The purpose of the present study was to examine the effects of cooperative training strategies to enhance students' socioscientific decision making as well as their metacognitive skills in the science classroom.
Bögeholz, Susanne, Eggert, Sabina, Hasselhorn, Marcus, Ostermeyer, Frauke   +3 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source