COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A novel hesitant fuzzy tensor-based group decision-making approach with application to heterogeneous wireless network evaluation. [PDF]
Bilal M, Lucian-Popa I.
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Enhanced fuzzy combined techniques for group decision-making with 2-tuple linguistic neutrosophic number and applications to sports event brand building evaluation. [PDF]
Lian J, Guo H, Hwan CK, Meng Y.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cognitive factors on the performance of group decision-making: a behavioral and eye-tracking study. [PDF]
Kexin C, Zuhua J, Jiapeng Y.
europepmc +1 more source
Group decision-making on risky choice in adolescents and young adults. [PDF]
Zhang W, Jiang Y, Wang C, Zhu L.
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Multi attribute group decision-making based on quasirung orthopair fuzzy Frank aggregation operators for optimal vehicle selection. [PDF]
Khan S +5 more
europepmc +1 more source

