Results 221 to 230 of about 15,130,985 (282)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Fermatean fuzzy score function and distance measure based group decision making framework for household waste recycling plant location selection. [PDF]

Sci Rep
Mishra AR, Rani P, Saeidi P, Deveci M, Alrasheedi AF.   +4 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Interpersonal heart rate synchrony predicts effective information processing in a naturalistic group decision-making task. [PDF]

Proc Natl Acad Sci U S A
Sharika KM, Thaikkandi S, Nivedita, Platt ML.   +3 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Research on the evaluation method of whole process engineering consulting service modes based on uncertain multiple-attribute group decision-making. [PDF]

Heliyon
Wang X, Hou Y, Peng J, Hu J.
europepmc   +1 more source

Utilizing sine trigonometric q-spherical fuzzy rough aggregation operators for group decision-making and their role in digital transformation. [PDF]

Heliyon
Azim AB, Ali A, Khan AS, Awwad FA, Ismail EAA, Ali S.   +5 more
europepmc   +1 more source

Small group decision making communication and the group process

, 1994
Fisher, B. Aubrey 1937-1986, Ellis, Donald G. 1947-   +1 more
core  

A novel incomplete hesitant fuzzy information supplement and clustering method for large-scale group decision-making. [PDF]

PeerJ Comput Sci
Wang J, Wang W, Meng F, Wang P, Wang X, Wei S, Liu T, Yang S.   +7 more
europepmc   +1 more source