Results 191 to 200 of about 36,439 (252)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Comparative Codon Usage Bias of CD2AP and BACH2 Across 49 Vertebrates: Implications for Porcine Macrophage Immunity in <i>Mycoplasma hyopneumoniae</i> Infection. [PDF]

Biology (Basel)
Li W, Wang P, Liu J, Xue X, Fan S, Ding Y, Zhang X, Yin Z, Zheng X.   +8 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Investigating the Impact of Pressure Relief Performance on the Occurrence of Pressure Injuries and Shoulder Pain in Wheelchair Users with Spinal Cord Injury (PRperf Study): Study Protocol for a Prospective Observational Study. [PDF]

Methods Protoc
Schürch Y, Hertig-Godeschalk A, Eriks-Hoogland I, Scheel-Sailer A, Brinkhof MWG, Arnet U.   +5 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Building the Future Curriculum for Emergency Medicine Residency Training. [PDF]

J Grad Med Educ
Regan L, McGee D, Davis F, Murano T.
europepmc   +1 more source

Anti-influenza drugs targeting trimeric RNA polymerase complex: From development to clinics. [PDF]

Acta Pharm Sin B
Li Y, Zhang J, He F, Cao C, Zhan Y, Zhong N, Yang Z.   +6 more
europepmc   +1 more source

The TEMP-PREVENT trial: a study protocol for a randomized, double-blind, placebo-controlled clinical trial of etidronate for treatment in young adult patients with pseudoxanthoma elasticum. [PDF]

Trials
Harmsen IM, Haverkamp M, van den Beukel TC, Kok M, de Jong PA, van Valen E, van Leeuwen R, Norel JO, Spiering W.   +8 more
europepmc   +1 more source

Design and analysis of a GaN-based 2D photonic crystal biosensor integrated with machine learning techniques for detection of skin diseases. [PDF]

Sci Rep
N H, A S.
europepmc   +1 more source

Healthcare use and its variation in people with fibromyalgia: a systematic review protocol. [PDF]

Prim Health Care Res Dev
Byrne AK, Twohig H, Muller S, Scott IC.
europepmc   +1 more source