Results 71 to 80 of about 2,511 (267)

A new class of group divisible designs with block size three

open access: yes, 1992
The elementary necessary conditions for the existence of a group divisible design with block size three, t groups of size g, and one group of size u are shown to be sufficient for all choices of g, t, and ...
Rees, Rolf   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

More about Divisible Design Graphs

open access: yes
: Divisible design graphs (DDG for short) have been recently defined by Kharaghani, Meulenberg and the second author as a generalization of (v, k, λ)-graphs.
Haemers, W.H., Crnkovic, D.
core  

An existence theorem for group divisible 3-designs of large order

open access: yes, 2011
In this paper we establish an asymptotic existence result for group divisible 3-designs of large order. Let k and u be positive integers, 3⩽k⩽u. Then there exists an integer m0=m0(k,u) such that there exists a group divisible 3-design of group type mu ...
Hedvig Mohácsy, Mohácsy, Hedvig
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Group divisible designs

open access: yes, 2020
Bu tez Gruplara Bü lunebilen Tasarımlar (GDD'ler) uzerinedir. GDD'ler Kombina-oü ütoryel Tasarımlar Teorisindeki ana yapılardan birisidir. GDD'ler ilk defa 1975'deHanani tarafından tanımlanmıs ve o gunden bu yana mesala PBD, Frame ve BIBDş ügibi kombinatoryel yapıların insaasında sıkca kullanılmıstır.ş ş şBir GDD (X, G, B) uclusu ...
openaire   +1 more source

Generalizing Clatworthy Group Divisible Designs

open access: yes, 2011
Clatworthy described the eleven group divisible designs with three groups, block size four, and replication number at most 10. Each of these can be generalized in natural ways. In this dissertation neat constructions are provided for these new families
Rogers, Julie
core  

A large order asymptotic existence theorem for group divisible 3-designs with index one

open access: yes, 2012
In this paper we prove that group divisible 3-designs exist for sufficiently large order with a fixed number of groups, fixed block size and index one, assuming that the necessary arithmetic conditions are satisfied. Let k and u be positive integers, 3≤k≤
Mohácsy, Hedvig
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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