Results 91 to 100 of about 15,144 (247)
Letter to the Editor: A List of New Group Divisible Designs. [PDF]
Sinha K.
europepmc +1 more source
Comparison of analysis methods and design choices for treatment-by-period interaction in unidirectional switch designs: a simulation study. [PDF]
Zhan Z, de Bock GH, van den Heuvel ER.
europepmc +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
On the Block Structure of Singular Group Divisible Designs
Shah [5] obtained an upper bound for the number of disjoint blocks in certain PBIB designs. The results obtained there [5] were based on theorems given in References [1], [3], and [6]. It should be pointed out here that theorems on Semi-Regular Group Divisible designs [5] are also implicitly given by Saraf [4].
openaire +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The efficient design of Nested Group Testing algorithms for disease identification in clustered data. [PDF]
Best AF, Malinovsky Y, Albert PS.
europepmc +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Discrete choice experiments: An overview on constructing D-optimal and near-optimal choice sets. [PDF]
Alamri AS, Georgiou S, Stylianou S.
europepmc +1 more source

