Results 111 to 120 of about 1,807,234 (313)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Group Psychosocial Interventions Following Acquired Brain Injury: A Systematic Review and Meta-analysis of Group Process and Outcomes [PDF]

Hannah L. McGlashan, Kate Thompson, Michael Lam, Tegan Cruwys, Zoe Walter, Elizabeth Beadle, Catherine Haslam   +6 more
openalex   +1 more source

P2‐362: Cognitive Intervention Design, Evaluation, and Reporting (CIDER): An International Working Group to Enhance the Quality of Cognition‐Focused Intervention Trials Targeting Older Adults [PDF]

, 2016
Alex Bahar‐Fuchs, Benjamin M. Hampstead, Sylvie Belleville, Tzvi Dwolatzky   +3 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evaluation of the effects of the social skills training method to children / Avaliação dos efeitos de uma modalidade de treinamento de habilidades sociais para crianças

Psicologia: Reflexão e Crítica, 2008
This article describes the effects of a social skills training on prosocial behavior, self concept, and peers acceptance, in three children: P.1, female, 9 years old, aggressive behavior and difficulty of learning; P.2, male, 7 years old, aggressive ...
Elaine Sabino Gonçalves, Sheila Giardini Murta   +1 more
doaj  

PS1-28: Optimizing Health Informatics Interventions From the Patient's Perspective: Focus Group on Improving Safe NSAID Use [PDF]

, 2010
D. Roblin, Richard M. Shewchuk, J. J Allison, Reji Varghese, Scott Baker, Catarina I. Kiefe   +5 more
openalex   +1 more source

Psychosocial Group Intervention

Alternation Interdisciplinary Journal for the Study of the Arts and Humanities in Southern Africa, 2023
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Examining the utility of assessment tools and group intervention programmes for mentally disordered offenders [PDF]

, 2011
Angharad Rees‐Jones
openalex  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source