Results 61 to 70 of about 16,434,534 (365)

Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality

Journal of Translational Medicine
Background Characterization of shared cancer mechanisms have been proposed to improve therapy strategies and prognosis. Here, we aimed to identify shared cell–cell interactions (CCIs) within the tumor microenvironment across multiple solid cancers and ...
Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Martin Smelik, Oleg Sysoev, Yunzhang Wang, A. K. M. Firoj Mahmud, Dina Mansour Aly, Mikael Benson   +8 more
doaj   +1 more source

The Cochrane Hepato-Biliary Group as a Resource Example of Evidence-Based Medicine for All

Acta Médica Portuguesa, 2013
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Dimitrinka Nikolova, Sarah Louise Klingenberg, Christian Gluud   +2 more
doaj   +1 more source

Group intervention with institutionalised older persons

HTS Teologiese Studies / Theological Studies, 2015
The number of older people in South Africa is increasing. This demands an increase in services by, inter alia, social workers and services by and within religious settings because of the special needs and challenges related to this particular life phase.
openaire   +6 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases

Scientific Reports
Multiomics analyses have identified multiple potential biomarkers of the incidence and prevalence of complex diseases. However, it is not known which type of biomarker is optimal for clinical purposes.
Martin Smelik, Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Oleg Sysoev, Firoj Mahmud, Dina Mansour Aly, Mikael Benson   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

The effectiveness of a group-based computerized HIV/STI prevention intervention for black women who use drugs in the criminal justice system: study protocol for E-WORTH (Empowering African-American Women on the Road to Health), a Hybrid Type 1 randomized controlled trial

Trials, 2018
Background This paper describes the study protocol of a hybrid type I randomized controlled trial that evaluates the effectiveness and cost-effectiveness of implementing Empowering African-American Women on the Road to Health (E-WORTH), an Afrocentric ...
Karen Johnson, Louisa Gilbert, Timothy Hunt, Elwin Wu, Lisa Metsch, Dawn Goddard-Eckrich, Stanley Richards, Rick Tibbetts, Jessica C. Rowe, Milton L. Wainberg, Nabila El-Bassel   +10 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

A preliminary study of collaborative group intervention with recovered peer supporters for eating disorders: Analyses including comparisons between in‐person and online sessions

PCN Reports
Aims This study aimed to evaluate the impacts of a single‐session group intervention for individuals with an eating disorder that involved collaborations between peer supporters, who had recovered from an eating disorder, and psychological professionals.
Yosuke Mochizuki, Tomoyo Isobe, Yuna Endo, Aina Iio, Kiyokazu Takebayashi, Hidenori Yamasue   +5 more
doaj   +1 more source