Results 61 to 70 of about 1,746,428 (216)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Supporting Parents of Youth with Chronic Pain: A Mixed Methods Evaluation of a Supportive Educational Intervention

open access: yesChildren
Background: Parents of youth with chronic health conditions face several challenges in supporting their children across contexts. Involvement of parents in a child’s pain management approach is accepted as best practice, yet there is little guidance on ...
Megan Mackenzie Sweeney   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The Psychological Capital of Left-Behind University Students: A Description and Intervention Study From China

open access: yesFrontiers in Psychology, 2018
The migrant worker phenomenon in China has negatively impacted the psychological development of these workers' children, whom researchers have termed “left-behind children” (LC) or university students with left-behind experience (USWL).
Li Liang   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Influence of Mediterranean and Western Dietary Patterns on Sensory Perception and Taste Sensitivity: A Study Among University Students

open access: yesFoods
This study examines the relationship between dietary patterns, specifically the Mediterranean diet (MD) and the Western diet (WD), and sensory perception among nursing students at the University of Valladolid, Spain.
Ghazal Zolfaghari   +5 more
doaj   +1 more source

Grupo de reflexão em saúde mental relacionada ao trabalho: uma contribuição da psicologia social do trabalho

open access: yesRevista Brasileira de Saúde Ocupacional, 2018
Resumo Objetivo: apresentar e discutir uma proposta de intervenção grupal com trabalhadores de uma indústria automobilística que apresentavam intenso sofrimento psíquico. Métodos: intervenção com métodos participativos, abrangendo 14 trabalhadores de
Mariana Pereira da Silva   +1 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Avaliação dos efeitos de uma modalidade de treinamento de habilidades sociais para crianças Evaluation of the effects of the social skills training method to children

open access: yesPsicologia: Reflexão e Crítica, 2008
Este artigo descreve os efeitos de uma intervenção em habilidades sociais sobre comportamentos pró-sociais, autoconceito e aceitação pelos pares, em três crianças: P.1, comportamento agressivo e dificuldade de aprendizagem, gênero feminino, 9 anos; P.2 ...
Elaine Sabino Gonçalves   +1 more
doaj   +1 more source

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