Results 71 to 80 of about 1,807,234 (313)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Influence of Mediterranean and Western Dietary Patterns on Sensory Perception and Taste Sensitivity: A Study Among University Students

Foods
This study examines the relationship between dietary patterns, specifically the Mediterranean diet (MD) and the Western diet (WD), and sensory perception among nursing students at the University of Valladolid, Spain.
Ghazal Zolfaghari, María José Castro-Alija, María Laguillo Diaz, Luis Carlos Ramón-Carreira, José María Jiménez, Irene Albertos   +5 more
doaj   +1 more source

The Psychological Capital of Left-Behind University Students: A Description and Intervention Study From China

Frontiers in Psychology, 2018
The migrant worker phenomenon in China has negatively impacted the psychological development of these workers' children, whom researchers have termed “left-behind children” (LC) or university students with left-behind experience (USWL).
Li Liang, Li Liang, Qianguo Xiao, Yisheng Yang   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

0600 Impact of Group-Based Sleep Apnea Management Intervention on Patient Reported Outcomes in Patients on Positive Airway Pressure for Obstructive Sleep Apnea [PDF]

, 2018
Mubbasher Syed, Tyler G. Kinzy, Reena Mehra, Douglas E. Moul, R Vanek, Tina Campean, Nancy Foldvary‐Schaefer, Harneet K. Walia   +7 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Grupo de reflexão em saúde mental relacionada ao trabalho: uma contribuição da psicologia social do trabalho

Revista Brasileira de Saúde Ocupacional, 2018
Resumo Objetivo: apresentar e discutir uma proposta de intervenção grupal com trabalhadores de uma indústria automobilística que apresentavam intenso sofrimento psíquico. Métodos: intervenção com métodos participativos, abrangendo 14 trabalhadores de
Mariana Pereira da Silva, Marcia Hespanhol Bernardo   +1 more
doaj   +1 more source

A multimodal group-based immersive virtual reality intervention for improving cognition and mental health in patients with post-covid-19 condition: A quasi-experimental design study. (Preprint)

, 2023
Bruno Porras-García, Neus Cano, Josep Gómez-Hernández, Mar Ariza, Toni Mora, David Roche, Maite Garolera   +6 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Avaliação dos efeitos de uma modalidade de treinamento de habilidades sociais para crianças Evaluation of the effects of the social skills training method to children

Psicologia: Reflexão e Crítica, 2008
Este artigo descreve os efeitos de uma intervenção em habilidades sociais sobre comportamentos pró-sociais, autoconceito e aceitação pelos pares, em três crianças: P.1, comportamento agressivo e dificuldade de aprendizagem, gênero feminino, 9 anos; P.2 ...
Elaine Sabino Gonçalves, Sheila Giardini Murta   +1 more
doaj   +1 more source