Results 51 to 60 of about 209,463 (265)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Structural volumetric and Periodic Table DTI patterns in Complex Normal Pressure Hydrocephalus—Toward the principles of a translational taxonomy

open access: yesFrontiers in Human Neuroscience
IntroductionWe previously proposed a novel taxonomic framework to describe the diffusion tensor imaging (DTI) profiles of white matter tracts by their diffusivity and neural properties.
Christine Lock   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Thermal and Photochemical Reactions of Organosilicon Compounds

open access: yesMolecules
This article provides a comprehensive review of quantum chemical computational studies on the thermal and photochemical reactions of organosilicon compounds, based on fundamental concepts such as initial complex formation, HOMO-LUMO interactions, and ...
Masae Takahashi
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

International Innovation Standards and Indexes

open access: yesRUDN Journal of Economics, 2011
The article deals with the OECD standards of innovation activity including Oslo Manual as well as Fraskati Manual and Canberra Manual. Particular attention is paid to the evolution of innovation metrics in 1950-2000.
D A Degterev
doaj  

Innovative Syntheses and Reactivity of Propiolamidines

open access: yesMolecules
Polydentate ligands with nitrogen donor atoms have possibly given rise to the largest group of coordination complexes described. Among these ligands, amidinates represent a nitrogenated version of carboxylates and allow the formation of complexes with ...
Carlos Ginés   +3 more
doaj   +1 more source

research Paper: Engineering the Electronic Properties of Buckyball Fullerene Nanostructures through Chemical Doping: Density Functional Theory Approach [PDF]

open access: yesفیزیک کاربردی ایران
Density functional theory (DFT) calculations show that the HOMO-LUMO gap of the buckyball fullerene is similar to the energy gap of a semiconductor. On the other hand, the buckyball is considered a candidate as a device for Moletronics.
Fatemeh Shiehzadeh   +2 more
doaj   +1 more source

Cation order control of correlations in double perovskite Sr_{2}VNbO_{6}

open access: yesPhysical Review Research, 2020
Double perovskites extend the design space for new materials and they often host phenomena that do not exist in their parent perovskite compounds. Here we present a detailed first-principles study of the correlated double perovskite Sr_{2}VNbO_{6}, where
Arpita Paul, Turan Birol
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

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