Results 101 to 110 of about 2,585,935 (304)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Report on Methodological Quality Assessment of Primary Care and General Practice Research in China in 2021: Quantitative Research, Systematic Review and Guidelines/Consensus Section [PDF]

open access: yes
Background At a time when healthcare reforms are being implemented in the new era, the scientific research output in the field of general practice and primary care in China has grown rapidly in recent years.
Quality Assessment Group for Quantitative Research, Systematic Review and Guidelines/Consensus of Chinese General Practice
core   +1 more source

De-implementing opioid prescribing in a dental group practice: Lessons learned. [PDF]

open access: yesCommunity Dent Oral Epidemiol, 2023
Rindal DB   +6 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Clinical Application of the Socket-Shield Concept in Multiple Anterior Teeth

open access: yesCase Reports in Dentistry, 2018
A case of rehabilitation of the upper front teeth is presented. To prevent bone resorption following extractions, a socket-shield technique on all the extracted teeth was performed.
G. Esteve-Pardo, L. Esteve-Colomina
doaj   +1 more source

Group mentoring in practice

open access: yesJournal of New Librarianship, 2018
This article examines the implementation of a group mentorship program by the New England Archivists, and considers the advantages and disadvantages of group mentoring.
Rose Oliveira
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Educating Practice Teachers and Specialist Practice Mentors for their new role: Ensuring high quality Practice Learning

open access: yes, 2014
This report presents the findings and deliverables from the Task and Finish Group on Health Visitor Practice Education established by Health Education England in February 2014.
Hall, Lynne   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Burden of allergic rhinitis in the United Kingdom

open access: yesFrontiers in Allergy
IntroductionAllergic rhinitis (AR) is a systemic respiratory condition that is associated with a considerable humanistic burden and is frequently underdiagnosed.
Michael Jones   +7 more
doaj   +1 more source

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