Results 81 to 90 of about 2,674,551 (218)

Experimental Characterization and First-Principles Calculations of Zn Segregation at the β″-Mg₅Al₂Si₄/Al Interfaces in Al-Mg-Si Alloys

Metals
In 6000-series Al-Mg-Si alloys, Zn is commonly added to enhance the aging response for improved properties. However, the segregation of Zn to interfaces and its interaction mechanisms with strengthening phases remain unclear.
Ying Li, Mingyang Yu, Wei Xiao, Yanan Li, Lizhen Yan, Rui Yu, Xiwu Li, Zhihui Li, Yongan Zhang, Baiqing Xiong   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Machine Learning Phase Prediction of Light-Weight High-Entropy Alloys Containing Aluminum, Magnesium, and Lithium

Metals
With the development of society, there is an increasingly urgent demand for light-weight, high-strength, and high-temperature-resistant structural materials.
Shenglong Li, Rui Liu, Hongwei Yan, Zhihui Li, Yanan Li, Xiwu Li, Yongan Zhang, Baiqing Xiong   +7 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Public behaviour in response to the COVID-19 pandemic: understanding the role of group processes. [PDF]

BJPsych Open, 2020
Drury J, Carter H, Ntontis E, Guven ST.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Simple and Effective Squash-PCR for Rapid Genotyping of Industrial Microalgae

Life
Microalgae are recognized for their versatility in providing renewable energy, biopharmaceuticals, and nutraceuticals, attributed to their sustainable, renewable, and cost-effective nature.
Guoliang Yuan, Song Gao, Jeffrey J. Czajka, Ziyu Dai, Kyle R. Pomraning, Rylan D. Duong, Beth A. Hofstad, Shuang Deng   +7 more
doaj   +1 more source

The Theory of Planned Behavior and the Social Identity Approach: A New Look at Group Processes and Social Norms in the Context of Student Binge Drinking. [PDF]

Eur J Psychol, 2020
Willis L, Lee E, Reynolds KJ, Klik KA.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source