Results 81 to 90 of about 3,506,344 (312)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

On Demand Responsiveness in Additive Cost Sharing [PDF]

We propose two new axioms of demand responsiveness for additive cost sharing with variable demands. Group Monotonicity requires that if a group of agents increase their demands, not all of them pay less.
Moulin, Herve, Sprumont, Yves
core  

Yritysvastuu tilinpäätöksessä : Tapiola-ryhmän yhtiöt 2007 - 2009 [PDF]

, 2011
Tämän tutkimuksen tarkoituksena oli selvittää, miten yritysvastuu näkyy Tapiola-ryhmän yhtiöiden tilinpäätöksissä vuosina 2007 – 2009. Tilinpäätöksissä keskityttiin tutkimaan yhtiöiden toimintakertomuksia.
Nieminen, Eerik
core  

Pathways to inflated responsibility beliefs in adolescent obsessive-compulsive disorder: a preliminary investigation [PDF]

, 2010
Background: An inflated sense of responsibility is characteristic of obsessive-compulsive disorder (OCD). No previous studies have investigated its origins. Five potential pathways to inflated responsibility beliefs have been proposed; these are tested
Lawrence, P. J. P., Williams, Tim I.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

EXPLORING THE CORRELATION BETWEEN CORPORATE SOCIAL RESPONSIBILITY INDICATORS AND CORPORATE REPUTATION : CASE STUDY OF LEGO GROUP 2012–2023

Modern Management Review
This study examines the correlation between Corporate Social Responsibility (CSR) indicators and LEGO Group’s corporate reputation from 2012 to 2023. Using quantitative analysis, the research investigates the relationship between key CSR metrics, such as
Mohamed BOULESNAM, Abdelghani KAHELA, Ouissam HOCINI   +2 more
doaj   +1 more source

An Exploratory Study into the Factors Impeding Ethical Consumption [PDF]

, 2011
Although consumers are increasingly engaged with ethical factors when forming opinions about products and making purchase decisions, recent studies have highlighted significant differences between consumers’ intentions to consume ethically, and their ...
A. Chatzidakis, A. Chatzidakis, A. Forte, A. Nicholls, A. Nicholls, A. Nicholls, A. Singhapakdi, A. Singhapakdi, B. Clavin, C. Barnett, C. Ford, C. Hines, C. Joergens, C. Strong, D. Sanfilippo, D. Shaw, D. Shaw, D. Shaw, D. Shaw, D. Shaw, D. Tomolillo, David Kilburn, E. Boulstridge, E. Cooper-Martin, E. Tsakiridou, G. Sproles, H. Berry, H. Cherrier, I. Ajzen, J. Hall, J. R. Rest, J. Whalen, Jeffery Bray, K. Webster, L. J. Marks, L. Kohlberg, L. Nash, M. Carrigan, M. Dickson, M. Dickson, M. Fishbein, M. Howard, M. J. OFallon, M. L. Loureiro, Nick Johns, P. Jones, P. M. Herr, P. Pelsmacker De, P. Pelsmacker De, P. Sparks, P. Sparks, P. Whysall, R. A. Krueger, R. Ford, R. McDevitt, S. Clouder, S. D. Hunt, S. J. Vitell, S. J. Vitell, S. J. Vitell, S. Steenhaut, T. Kent, T. Loe, T. M. Jones, Y-K. Kim   +64 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source