In vitro γ-aminobutyric acid A (GABA<sub>A</sub>) receptor activity and binding interactions at the α<sup>+</sup>/γ<sub>2</sub><sup>-</sup> interface of 53 prescription and designer benzodiazepines. [PDF]
Norman C +4 more
europepmc +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Study and Application of a New Casing Protection Technology for Long-Term Gas Extraction in Deep Coal Seams. [PDF]
Li H, Cui J, Lu P, Yang J, Zhang J.
europepmc +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
Dialkylaminoalkylation of β-ketosulfones via ring-opening of 3-sulfonylpyrrolidines. [PDF]
Buev EM +3 more
europepmc +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
In Silico Destructive Activity of Phytochemicals From Ocimum sanctum Against the T9SS Proteins of Porphyromonas gingivalis. [PDF]
H V +5 more
europepmc +1 more source
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
Investigating the Protonated Cannabinoid Dimer Detected in the Forensic Analysis of <i>Cannabis</i> by DART-MS: A Combined Mass Spectrometry and Computational Study. [PDF]
Arathala P +4 more
europepmc +1 more source

