Results 211 to 220 of about 665,695 (311)

Probing Flavonoid-Metal and Membrane Interactions by UV-Vis Spectroscopy: Structural Insights into Bioactivity and Bioavailability. [PDF]

Membranes (Basel)
Gong S, Ou X.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Zerovalent transition-metal inverse-sandwich complexes of a diborataanthracene dianion. [PDF]

Chem Sci
Gerstner A, Arrowsmith M, Dietz M, Mihm C, Braunschweig H.   +4 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The mechanism of Tat-dependent protein translocation. [PDF]

Microb Cell
Brüser T, Sanders C.
europepmc   +1 more source

Quantum Codes from Group Ring Codes

This article examines group ring codes over finite fields and finite groups. We also present a section on two-dimensional cyclic codes in the quotient ring F q [x, y]/⟨x l -1, y m -1⟩.
Bag, Tushar, Abdukhalikov, Kanat, Panario, Daniel   +2 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The effect of silicone ring tourniquet in anterior cruciate ligament reconstruction: a retrospective comparative study. [PDF]

BMC Musculoskelet Disord
Shen X, Lu M, Yang W, Xu S, Sun G.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Associated Urogenital Injuries Following Pelvic Trauma in Pediatrics: A 15-Year Single-Center Retrospective Study. [PDF]

Cureus
Van Wagoner C, Shumway T, Saroyan A, Saleh L, Hasan S, Chrumka A, Saleh E.   +6 more
europepmc   +1 more source