Results 51 to 60 of about 278,857 (261)

Group-specific archaeological signatures of stone tool use in wild macaques

eLife, 2019
Stone tools in the prehistoric record are the most abundant source of evidence for understanding early hominin technological and cultural variation. The field of primate archaeology is well placed to improve our scientific knowledge by using the tool ...
Lydia V Luncz, Mike Gill, Tomos Proffitt, Magdalena S Svensson, Lars Kulik, Suchinda Malaivijitnond   +5 more
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On multipolar magnetic anomaly detection: multipolar signal subspaces, an analytical orthonormal basis, multipolar truncation and detection performance

EURASIP Journal on Advances in Signal Processing
In this paper, we consider the magnetic anomaly detection problem which aims to find ferromagnetic masses by estimating the weak perturbation they induce on local Earth’s magnetic field.
Clément Chenevas-Paule, Steeve Zozor, Laure-Line Rouve, Olivier J. J. Michel, Olivier Pinaud, Romain Kukla   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Low Concordance between Gene Expression Signatures in ER Positive HER2 Negative Breast Carcinoma Could Impair Their Clinical Application.

PLoS ONE, 2016
BackgroundNumerous prognostic gene expression signatures have been recently described. Among the signatures there is variation in the constituent genes that are utilized.
Enora Laas, Peter Mallon, Francois P Duhoux, Amina Hamidouche, Roman Rouzier, Fabien Reyal   +5 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Heisenberg Group-Based Digital Signatures for Secure Communications

IEEE Access
This paper proposes a new digital signature algorithm that employs the Heisenberg group over a prime field and exploits its structure to provide strong cryptographic properties. The developed scheme involves the Heisenberg group within a commutator-based
Najla Althuniyan, Ahmed Alamer, Awais Yousaf, Muhammad Waseem, Sarah Aljohani   +4 more
doaj   +1 more source

Quasi-Efficient Revocation of Group Signatures [PDF]

, 2003
A group signature scheme allows any group member to sign on behalf of the group in an anonymous and unlinkable fashion. In the event of a dispute, a designated trusted entity can reveal the identity of the signer. Group signatures are claimed to have many useful applications such as voting and electronic cash.
ATENIESE, GIUSEPPE, Dawn Song, Gene Tsudik   +2 more
openaire   +1 more source