Results 221 to 230 of about 1,525,569 (308)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Effect of a tea tree oil mouthwash on plaque-induced gingivitis when comparing to chlorhexidine: an exploratory randomised clinical trial. [PDF]

Front Oral Health
Menat A, Rozan C, Barroso H, Proença L, Salema-Oom M, Botelho J, Zhiri A, Manso AC.   +7 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Association between neurodegenerative plasma biomarkers and geriatric depression in older adults with and without clinical dementia in Kinshasa, Democratic Republic of the Congo. [PDF]

Front Psychiatry
Tsengele N, Sodi Magudigana A, Gikelekele G, Epenge E, Kangula G, Vukumuna EM, Bilongo AM, Mbuku Nguala S, Bomba DB, Mananga Lelo G, N'situ Mankubu A, Ikanga J.   +11 more
europepmc   +1 more source

Straightened Small Pinnae in TRPV4 c.1024G>T Heterozygous Cats. [PDF]

Anim Genet
Matsumoto Y, Ishii R, Ukawa H, Hiyoshi-Kanemoto S, Hayashi H, Onishi H, Ataka K, Horie R.   +7 more
europepmc   +1 more source

Types of physical activity and applied outcome measures in physical activity interventions among patients with inflammatory bowel disease: a scoping review. [PDF]

BMC Gastroenterol
Fromberg EB, Brink MT, Villumsen M, Thomsen T, Poulsen A, Aadahl M.   +5 more
europepmc   +1 more source

Immunogenicity and safety of co-administered <i>Escherichia coli</i>-produced bivalent HPV-16/18 vaccine and hepatitis E vaccine. [PDF]

Front Immunol
Yan R, Cen M, Zhou Y, Ma L, Zhou X, He H, Qi X, Tang X, Liang H, Chen Y, Qi J, Yang S.   +11 more
europepmc   +1 more source