Results 61 to 70 of about 1,525,569 (308)

The death of reflective supervision? An exploration of the role of reflection within supervision in a Local Authority Youth Offending Service [PDF]

, 2014
Reflection within supervision has been identified as key to effective social work practice (Munro, 2011). However, despite the tradition of supervision being strongly embedded in youth justice practice, other imperatives, such as audit monitoring and ...
Taylor, Rhian
core  

Research on Intelligent Control Platform in Urban Rail Transit FAO Scenario

Chengshi guidao jiaotong yanjiu
[Objective] The existing operational mechanisms primarily rely on operational management systems that drive personnel to perform operational tasks. Operational staff communicate information through phones or intercom devices and issue operational control
Chunming ZHANG
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Shaping supervision practice through research: Effects of supervision for counselling practice

, 2007
That there are links between effective supervision and effective counselling practice tends to be taken for granted. As a contribution to documenting the professional knowledges and experiences that might stand behind the profession’s claims for the ...
Rodwell, Jan, Riches, Val, Flintoff, Vivianne, Rewita, Titihuia, Overdyck, Helga, McLachlan, Debbie, Crocket, Kathie, Gaddis, Stephen, Schoffelmeer, Ellie, Day, Caroline, Malcolm, Pam, Lammers, Marianne   +11 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The effectiveness of banking supervision

, 2009
Banking supervision is an essential aspect of modern financial systems, seeking crucially to monitor risk-taking by banks so as to protect depositors, the government safety net and the economy as a whole against systemic bank failure and its consequences.
Davis, EP, Obasi, U
core  

Group process variables in group supervision [PDF]

, 1994
The purpose of this study was to systematically investigate process components during actual group supervision with the purpose of targeting process variables that could serve as a basis for further research regarding critical components of group ...
Werstlein, Pamela Odham, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Coupling Characteristics of Operational Safety Risks in Urban Rail Transit

Chengshi guidao jiaotong yanjiu
Objective Urban rail transit system is a complex integrated system involving people, machine, environment, and management, with its operational risks existing not independently or statically.
SHI Ting
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source