Results 81 to 90 of about 19,581,970 (268)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Watershed planning initiative: Science and Technology Task Group, Final report

open access: yes, 1997
The Science and Technology Task Group (the Task Group) attempted to address four questions: 1) Is there a need for watershed planning in Ontario?; 2) What is state-of-the-art science in watershed planning?; 3) Is state-of-the-art science being applied to
Science and Technology Task Group
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Antea Group Archeologie 2015/32

open access: yes, 2016
Voorliggend onderzoeksrapport betreft de verslaglegging van diverse archeologische onderzoeken die met elkaar gemeen hebben dat ze alle drie gelegen zijn in de kern van Zevenbergen. Als eerste deelgebied wordt hier de haven onderscheiden.
Koopmanschap, Dr. H.J.L.C. (Antea Group)
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Collaborative Modeling of Group Learning Applications Using Eclipse Technology

open access: yesProceedings, 2019
The design and creation of groupware tools is a complex task that usually requires the participation of different stakeholders (software engineers, designers, etc.), either working at the same time or collaborating asynchronously. This paper describes an
Yoel Arroyo   +4 more
doaj   +1 more source

Antea Group Archeologie 2021/50

open access: yes, 2022
Antea Group projectnummer 454718. Op 18 februari 2020 voerde Antea Group Archeologie een archeologische begeleiding uit aan de Hereweg en omgeving te Bierum, in de gemeente Delfzijl.
Thasing, S. (Antea Group)   +1 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Resource Allocation and Minmax Scheduling Under Group Technology and Different Due-Window Assignments

open access: yesAxioms
This article investigates single-machine group scheduling integrated with resource allocation under different due-window (DIFDW) assignment. Three distinct scenarios are examined: one with constant processing times, one with a linear resource consumption
Li-Han Zhang, Ji-Bo Wang
doaj   +1 more source

24. Developing an Educational Technology Group for Pre-Service Teachers

open access: yesCollected Essays on Learning and Teaching, 2012
The College of Education Technology Group is a pilot program that supports teacher candidates in developing an understanding of the integration of technology.
Jay Wilson
doaj   +1 more source

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