Results 141 to 150 of about 324,883 (267)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Binge-drinking: A test of the role of group norms in the Theory of Planned Behaviour
, 2003 A study was undertaken to assess the utility of the theory of planned behaviour in the prediction of students’ binge-drinking. Additionally, a social identity theory/self-categorization theory perspective was utilised to address the usually weak ...
Johnston, Kim L., White, Katy M.
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Dieudonné theory for Faltings' strict ϭ-modules [PDF]
, 2005 The theory of group schemes and their liftings to mixed characteristic valuation rings is well-developed. In [Fal02], a new equi-characteristic analogue of group schemes, known as group schemes with strict ๕-action, or strict ๕-modules, was proposed and ...
Gibbons, William
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The automation of SMEFT-assisted constraints on UV-complete models
Journal of High Energy PhysicsThe ongoing Effective Field Theory (EFT) program at the LHC and elsewhere is motivated by streamlining the connection between experimental data and UV-complete scenarios of heavy new physics beyond the Standard Model (BSM). This connection is provided by
Jaco ter Hoeve +4 more
doaj +1 more source
Characterization of entanglement transformation via group representation theory
, 2003 Entanglement transformation of composite quantum systems is investigated in the context of group representation theory. Representation of the direct product group SL(2, C) circle times SL(2, C), composed of local operators acting on the binary composite ...
yyan@ust.hk +4 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Group covers and partitions : covering and partition numbers [PDF]
, 2013 A group cover is a collection of subgroups whose union is the group. A group partition is a group cover in which the elements have trivial pairwise intersection.
NC DOCKS at Western Carolina University +1 more
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